# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3802755 | B | Inhibition of endoplasmic reticulum stress-induced CHOP activity in tunicamycin-treated rat INS-1 cells assessed as DNA fragmentation at 20 uM after 24 hrs by TUNEL assay (Rvb = 15%) | Rattus norvegicus | 1 | ALA3797120 | cell-based format | Scientific Literature | |
2. | ALA3802756 | B | Inhibition of endoplasmic reticulum stress-induced CHOP activity in rat INS-1 cells assessed as suppression of tunicamycin-induced PARP cleavage at 20 uM after 2 to 24 hrs by Western blot method | Rattus norvegicus | 1 | ALA3797120 | cell-based format | Scientific Literature | |
3. | ALA3802757 | B | Inhibition of endoplasmic reticulum stress-induced CHOP activity in rat INS-1 cells assessed as suppression of tunicamycin-induced caspase-3 cleavage at 20 uM after 2 to 24 hrs by Western blot method | Rattus norvegicus | 1 | ALA3797120 | cell-based format | Scientific Literature | |
4. | ALA3802758 | B | Inhibition of endoplasmic reticulum stress-induced CHOP activity in rat INS-1 cells assessed as decrease in brefeldin A-induced cell death by measuring cell viability at 5 to 20 uM after 72 hrs by CellTiter-Glo assay | Rattus norvegicus | 1 | ALA3797120 | cell-based format | Scientific Literature | |
5. | ALA3802760 | B | Inhibition of endoplasmic reticulum stress-induced CHOP activity in rat INS-1 cells assessed as decrease in sodium palmitate-induced cell death by measuring cell viability at 2.5 to 20 uM after 72 hrs by CellTiter-Glo assay | Rattus norvegicus | 1 | ALA3797120 | cell-based format | Scientific Literature | |
6. | ALA3802762 | B | Inhibition of endoplasmic reticulum stress-induced CHOP activity in rat INS-1 cells assessed as restoration of tunicamycin-mediated reduction of 20 mM glucose-stimulated insulin secretion preincubated for 24 hrs followed by glucose addition and subsequent incubation for 45 mins by ELISA | Rattus norvegicus | 1 | ALA3797120 | cell-based format | Scientific Literature |