# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3803643 | B | Inhibition of DprE1 in mixture of Mycobacterium smegmatis MC2 155 membrane and cell envelope fractions assessed as incorporation of P[14C]RPP into [14C]-decaprenylphosphoryl arabinose up to 0.6 mM incubated for 1 hr by TLC/autoradiographic method | Mycolicibacterium smegmatis MC2 155 | 2 | ALA3797190 | assay format | Scientific Literature | |
2. | ALA3806433 | B | Inhibition of DprE1 in P-14C-RPP-labelled Mycobacterium smegmatis MC2 155 cell membranes assessed as supression of conversion of decaprenylphosphoryl ribose to decaprenylphosphoryl arabinose after 1 hr by TLC analysis | Mycolicibacterium smegmatis MC2 155 | 3 | ALA3804812 | cell-based format | Scientific Literature | |
3. | ALA4375667 | B | Inhibition of DprE1 in Mycolicibacterium smegmatis MC2 155 lysate assessed as reduction in epimerization of P[14C]RPP to DP[14C]A at 700 uM measured after 1.5 hrs in presence of NADH by TLC-based autoradiography | Mycolicibacterium smegmatis MC2 155 | 6 | ALA4373711 | subcellular format | Scientific Literature | |
4. | ALA4375668 | B | Inhibition of DprE1 in Mycolicibacterium smegmatis MC2 155 lysate assessed as reduction in epimerization of P[14C]RPP to DP[14C]A at 70 uM measured after 1.5 hrs in presence of NADH by TLC-based autoradiography | Mycolicibacterium smegmatis MC2 155 | 1 | ALA4373711 | subcellular format | Scientific Literature | |
5. | ALA5139587 | B | Inhibition of N-terminal thioredoxin-tagged Mycobacterium smegmatis DprE1 expressed in Escherichia coli BL21(DE3) incubated for 7 days by microplate alamar blue assay | Mycolicibacterium smegmatis | 1 | ALA5137025 | assay format | Scientific Literature |