# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3816047 | B | Agonist activity at mouse GPR174 expressed in HEK293FT cells after 1.5 hrs by alkaline phosphatase tagged-TGFalpha shedding assay | Mus musculus | 12 | cell-based format | Scientific Literature | ||
2. | ALA4807191 | F | Inhibition of mouse GPR174 in anti-CD3/antiCD28-stimulated mouse splenocytes assessed as increase in IL-2 production at 10 uM measured after 2 days | Mus musculus | 1 | tissue-based format | Patent Bioactivity Data | ||
3. | ALA5151739 | F | Agonist activity at mouse GPR174 transfected in human HEK293FT cells co-transfected with AP-TGFalpha assessed as AP-TGFalpha release incubated for 90 mins by TGFalpha shedding assay | Mus musculus | 21 | cell-based format | Scientific Literature | ||
4. | ALA5151740 | F | Agonist activity at mouse GPR174 transfected in human HEK293FT cells co-transfected with AP-TGFalpha assessed as AP-TGFalpha release incubated for 90 mins by TGFalpha shedding assay relative to LysoPS(18:1) | Mus musculus | 16 | cell-based format | Scientific Literature | ||
5. | ALA5151741 | F | Partial agonist activity at mouse GPR174 transfected in human HEK293FT cells co-transfected with AP-TGFalpha assessed as AP-TGFalpha release incubated for 90 mins by TGFalpha shedding assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
6. | ALA5151742 | F | Partial agonist activity at mouse GPR174 transfected in human HEK293FT cells co-transfected with AP-TGFalpha assessed as AP-TGFalpha release incubated for 90 mins by TGFalpha shedding assay relative to LysoPS(18:1) | Mus musculus | 6 | cell-based format | Scientific Literature | ||
7. | ALA5151743 | F | Antagonist activity at mouse GPR174 transfected in human HEK293FT cells co-transfected with AP-TGFalpha assessed as inhibition of LysoPalloT-NH-C3-ph-m-O-C11-induced AP-TGFalpha release incubated for 90 mins by TGFalpha shedding assay | Mus musculus | 22 | cell-based format | Scientific Literature | ||
8. | ALA5151744 | F | Antagonist activity at mouse GPR174 transfected in human HEK293FT cells co-transfected with AP-TGFalpha assessed as inhibition of LysoPalloT-NH-C3-ph-m-O-C11-induced AP-TGFalpha release incubated for 90 mins by TGFalpha shedding assay relative to control | Mus musculus | 21 | cell-based format | Scientific Literature | ||
9. | ALA5151745 | F | Inverse agonist activity at mouse GPR174 transfected in human HEK293FT cells co-transfected with AP-TGFalpha assessed as inhibition of LysoPalloT-NH-C3-ph-m-O-C11-induced AP-TGFalpha release incubated for 90 mins by TGFalpha shedding assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
10. | ALA5151746 | F | Inverse agonist activity at mouse GPR174 transfected in human HEK293FT cells co-transfected with AP-TGFalpha assessed as inhibition of LysoPalloT-NH-C3-ph-m-O-C11-induced AP-TGFalpha release incubated for 90 mins by TGFalpha shedding assay relative to control | Mus musculus | 1 | cell-based format | Scientific Literature |