# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4381086 | Binding | Binding affinity to NRAS RNA g-quadruplex (unknown origin) by fluorescence spectroscopy | Not specified | 3 | ALA4376882 | nucleic acid format | Scientific Literature | |
2. | ALA4381087 | Binding | Binding affinity to human KRAS utr-1 RNA g-quadruplex by fluorescence spectroscopy | Homo sapiens | 3 | ALA4376882 | nucleic acid format | Scientific Literature | |
3. | ALA4381088 | Binding | Binding affinity to human KRAS utr-c RNA g-quadruplex by fluorescence spectroscopy | Homo sapiens | 3 | ALA4376882 | nucleic acid format | Scientific Literature | |
4. | ALA4381089 | Binding | Binding affinity to human KRAS utr-z RNA g-quadruplex by fluorescence spectroscopy | Homo sapiens | 3 | ALA4376882 | nucleic acid format | Scientific Literature | |
5. | ALA4381090 | Binding | Binding affinity to human KRAS utr-z RNA g-quadruplex assessed as induction of hypochromicity at 1.6 uM by UV-vis spectrophotometry relative to control | Homo sapiens | 1 | ALA4376882 | nucleic acid format | Scientific Literature | |
6. | ALA4381092 | Binding | Binding affinity to human KRAS utr-z RNA g-quadruplex assessed as emission spectra at absorbance 650 to 715 nm 1 uM by fluorescence titration method | Homo sapiens | 1 | ALA4376882 | nucleic acid format | Scientific Literature | |
7. | ALA4381093 | Binding | Binding affinity to NRAS RNA g-quadruplex (unknown origin) at 40 degree C by SPR analysis | Not specified | 4 | ALA4376882 | nucleic acid format | Scientific Literature | |
8. | ALA4381094 | Binding | Binding affinity to human KRAS utr-z RNA g-quadruplex at 40 degree C by SPR analysis | Homo sapiens | 4 | ALA4376882 | nucleic acid format | Scientific Literature | |
9. | ALA4381095 | Binding | Binding affinity to human KRAS utr-z RNA g-quadruplex assessed as compound-RNA complex stoichiometry ratio of 6:1 by Job's plot analysis | Homo sapiens | 1 | ALA4376882 | nucleic acid format | Scientific Literature | |
10. | ALA4381096 | Binding | Binding affinity to human KRAS utr-z RNA g-quadruplex assessed as compound-RNA complex stoichiometry ratio of 9:1 by Job's plot analysis | Homo sapiens | 1 | ALA4376882 | nucleic acid format | Scientific Literature | |
11. | ALA4381097 | Binding | Binding affinity to human KRAS utr-z RNA g-quadruplex assessed as compound-RNA complex stoichiometry ratio of 4:1 by Job's plot analysis | Homo sapiens | 1 | ALA4376882 | nucleic acid format | Scientific Literature | |
12. | ALA4381099 | Binding | Binding affinity to human KRAS utr-z RNA g-quadruplex assessed as compound-RNA complex stoichiometry ratio of 1:1 by Job's plot analysis | Homo sapiens | 1 | ALA4376882 | nucleic acid format | Scientific Literature | |
13. | ALA4381115 | Binding | Induction of ROS-mediated Cys5.5 labeled Ras RNA g-quadruplex (unknown origin) degradation at 0.6 uM incubated for 30 mins in presence of NAC followed by photoirradiation for 15 to 30 mins by PAGE analysis | Not specified | 1 | ALA4376882 | nucleic acid format | Scientific Literature | |
14. | ALA4381116 | Binding | Induction of ROS-mediated Cys5.5 labeled Ras RNA g-quadruplex (unknown origin) degradation assessed as residual RNA g-quadruplex at 0.6 uM incubated for 15 to 30 mins followed by photoirradiation for 30 mins by PAGE analysis relative to control | Not specified | 1 | ALA4376882 | nucleic acid format | Scientific Literature | |
15. | ALA4381117 | Binding | Induction of ROS-mediated Cys5.5 labeled Ras RNA g-quadruplex (unknown origin) degradation assessed as increase in residual RNA g-quadruplex at 0.6 uM incubated for 30 mins in presence of NAC followed by photoirradiation for 15 to 30 mins by PAGE analysis relative to control | Not specified | 1 | ALA4376882 | nucleic acid format | Scientific Literature | |
16. | ALA4372388 | Binding | Binding affinity to cMYC G-quadruplex DNA (unknown origin) in tris-KCL buffer by fluorimetric titration assay | Not specified | 3 | ALA4371043 | nucleic acid format | Scientific Literature | |
17. | ALA4372389 | Binding | Binding affinity to 6-FAM/TAMRA labeled cMYC G-quadruplex DNA (unknown origin) in potassium cacodylate buffer assessed as change in melting temperature at 1 uM at pH 7.4 by FRET-Based DNA melting assay | Not specified | 10 | ALA4371043 | nucleic acid format | Scientific Literature | |
18. | ALA4372391 | Binding | Binding affinity to 6-FAM/TAMRA labeled cMYC G-quadruplex DNA (unknown origin) in potassium cacodylate buffer assessed as change in melting temperature at 1 uM at pH 7.4 in presence of 1 to 200 equiv calf thymus DNA by FRET-Based DNA melting assay | Not specified | 1 | ALA4371043 | nucleic acid format | Scientific Literature | |
19. | ALA4372392 | Binding | Effect on native parallel topology of cMYC G-quadruplex DNA (unknown origin) assessed as formation of positive band at 260 nm up to 10 equiv concentration by CD spectroscopy | Not specified | 1 | ALA4371043 | nucleic acid format | Scientific Literature | |
20. | ALA4372393 | Binding | Effect on native parallel topology of cMYC G-quadruplex DNA (unknown origin) assessed as formation of negative band at 240 nm up to 10 equiv concentration by CD spectroscopy | Not specified | 1 | ALA4371043 | nucleic acid format | Scientific Literature |