| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1804657 | B | Inhibition of tubulin alpha in human SH-SY5Y cells assessed as inhibition of tubulin alpha polymerization at 3 times IC50 value after 24 hrs by immunofluorescence | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA1804658 | B | Inhibition of tubulin alpha polymerization in human HeLa cells assessed as decreased pelletable tubulin alpha fraction at 3 times IC50 value after 16 hrs by Western blotting in presence of paclitaxel | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA1804659 | B | Inhibition of tubulin alpha polymerization in human HeLa cells assessed as increase in soluble tubulin alpha fraction at 3 times IC50 value after 16 hrs by Western blotting in presence of paclitaxel | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA2341488 | B | Binding affinity to Tubulin alpha/beta in human BT-483 cells assessed as microtubule depolymerization at 1 uM after 6 hrs by immunofluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2341489 | B | Binding affinity to Tubulin alpha/beta in human BT-483 cells assessed as microtubule depolymerization at 3.6 uM after 6 hrs by immunofluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2432698 | B | Inhibition of tubulin-alpha (unknown origin) polymerization by fluorescence-based assay | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 7. | ALA3388602 | B | Inhibition of tubulin alpha in human LoVo cells assessed as effect on microtubule spindles at 20 nM after 24 hrs | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA3388603 | B | Inhibition of tubulin alpha in human LoVo cells assessed as effect on microtubule spindles at 100 nM after 24 hrs | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA3388604 | B | Inhibition of tubulin alpha in human LoVo cells assessed as effect on tubulin intensity level at 20 nM | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3388605 | B | Inhibition of tubulin alpha in human LoVo cells assessed as effect on tubulin intensity level at 100 nM | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3803220 | F | Induction of phenotypic perturbation in human ONS cells assessed as increase in apha tubulin marker at 10 uM after 24 hrs by alpha tubulin staining based assay relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 12. | ALA3881712 | B | Induction of alpha-tubulin depolymerization in HUVEC at 200 nM measured after 30 mins by DAPI staining based indirect immunofluorescence analysis | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
| 13. | ALA4362716 | B | Induction of microtubule depolymerization in human CL1-0 cells assessed as increase in alpha tubulin soluble form by immunoblot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4362717 | B | Induction of microtubule depolymerization in human NCI-H1975 cells assessed as increase in alpha tubulin soluble form by immunoblot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4370494 | B | Inhibition of tubulin alpha in human A2780 cells assessed as reduction in cell growth | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4370495 | B | Inhibition of tubulin alpha in human A2780 cells assessed as cell growth inhibition after 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4370496 | B | Inhibition of tubulin alpha in human A2780CP cells assessed as cell growth inhibition after 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA4384461 | B | Disruption of alpha-tubulin in human BT549 cells at 10 uM after 6 hrs by FITC/DAPI staining-based confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4384463 | B | Disruption of alpha-tubulin in human BT549 cells assessed as loss of cellular structure at 10 uM after 6 hrs by FITC/DAPI staining-based confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4384464 | B | Disruption of alpha-tubulin in human BT549 cells assessed as formation of cellular rounding at 10 uM after 6 hrs by FITC/DAPI staining-based confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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