| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1175683 | B | inhibition of beta tubulin acylation in human M21 cells assessed as beta-tubulin band migration by Western blotting | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 2. | ALA2421070 | B | Inhibition of [3H] radiolabelled colchicine binding to tubulin beta (unknown origin) at 1 uM by DEAE-cellulose filter method | Homo sapiens | 3 | protein format | Scientific Literature | ||
| 3. | ALA2421071 | B | Inhibition of [3H] radiolabelled colchicine binding to tubulin beta (unknown origin) at 5 uM by DEAE-cellulose filter method | Homo sapiens | 3 | protein format | Scientific Literature | ||
| 4. | ALA5253919 | B | Binding affinity to colchicine binding site of beta-tubulin in human MCF7 cells assessed as inhibition of beta-tubulin-EBI adduct formation at 10 uM pretreated for 2 hrs followed by EBI addition and measured after 1.5 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA5253920 | B | Binding affinity to colchicine binding site of beta-tubulin in human HT-29 cells assessed as inhibition of beta-tubulin-EBI adduct formation at 10 uM pretreated for 2 hrs followed by EBI addition and measured after 1.5 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3226418 | B | Inhibition of tubulin beta in human PC3 cells assessed as multiple spindle-poles formation at 100 nM after 24 hrs by DAPI-staining based immunofluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3226419 | B | Inhibition of tubulin beta in human PC3 cells assessed as chromosomal overduplication at 100 nM after 24 hrs by DAPI-staining based immunofluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3592912 | B | Binding affinity to Tubulin beta in human M21 cells assessed as tubulin acylation at 1500 nM after 24 hrs by electrophoretic mobility shift assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA3592913 | B | Binding affinity to Tubulin beta in human M21 cells assessed as tubulin acylation at 3100 nM after 24 hrs by electrophoretic mobility shift assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3592914 | B | Binding affinity to Tubulin beta in human M21 cells assessed as tubulin acylation at 4100 nM after 24 hrs by electrophoretic mobility shift assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3592915 | B | Inhibition of N,N-ethylene-bis(iodoacetamide) binding to Tubulin beta colchicines-binding site in human M21 cells assessed as adduct formation at 410 nM by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA3592916 | B | Inhibition of N,N-ethylene-bis(iodoacetamide) binding to Tubulin beta colchicines-binding site in human M21 cells assessed as adduct formation at 910 nM by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA3592917 | B | Inhibition of N,N-ethylene-bis(iodoacetamide) binding to Tubulin beta colchicines-binding site in human M21 cells assessed as adduct formation at 2500 nM by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA3592918 | B | Inhibition of N,N-ethylene-bis(iodoacetamide) binding to Tubulin beta colchicines-binding site in human M21 cells assessed as adduct formation at 100000 nM by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA4313578 | B | Inhibition of tubulin beta polymerization in human HepG2 cells at IC50 using TMB substrate preincubated for 2 hrs followed by substrate addition measured after 15 to 20 mins in presence of GTP by ELISA relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA4362731 | B | Binding affinity to beta tubulin in human NCI-H1975 cells incubated for overnight by immunoblotting based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4384462 | B | Disruption of beta-tubulin in human BT549 cells at 10 uM after 6 hrs by FITC/DAPI staining-based confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4384465 | B | Disruption of beta-tubulin in human BT549 cells assessed as loss of cellular structure at 10 uM after 6 hrs by FITC/DAPI staining-based confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4384466 | B | Disruption of beta-tubulin in human BT549 cells assessed as formation of cellular rounding at 10 uM after 6 hrs by FITC/DAPI staining-based confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4384470 | B | Disruption of beta-tubulin in human BT549 cells assessed as short microtubule at 20 uM after 6 hrs by FITC/DAPI staining-based confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!