# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3738515 | B | Inhibition of Staphylococcus aureus ATCC 35556 SecA1 expressed in Escherichia coli BL21-gammaDE3 assessed as reduction in intrinsic ATPase activity incubated for 3 hrs measured by malachite green colorimetric method | Staphylococcus aureus | 3 | ALA3734668 | assay format | Scientific Literature | |
2. | ALA3738517 | B | Inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposomal ion channel activity in Xenopus laevis oocytes incubated for 3 hrs measured by recording ion current for 1 min | Staphylococcus aureus | 3 | ALA3734668 | cell-based format | Scientific Literature | |
3. | ALA3738518 | B | Non-competitive inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposomal ATPase activity in Xenopus laevis oocytes incubated for 3 hrs measured by Lineweaver-Burk plot analysis | Staphylococcus aureus | 2 | ALA3734668 | cell-based format | Scientific Literature | |
4. | ALA3738519 | B | Inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposome dependent proOmpA translocation incubated for 1.5 hrs measured by Western blot analysis | Staphylococcus aureus | 1 | ALA3734668 | single protein format | Scientific Literature | |
5. | ALA3738520 | B | Binding affinity to SecA1 in Staphylococcus aureus ATCC 6538 whole cell lysate incubated for 1 hr by Streptavidin-based pull down assay | Staphylococcus aureus | 1 | ALA3734668 | assay format | Scientific Literature | |
6. | ALA3738523 | B | Inhibition of Staphylococcus aureus SecA1 assessed as reduction in secretion of alpha-hemolysin at 10 uM by Western blot analysis | Staphylococcus aureus | 1 | ALA3734668 | single protein format | Scientific Literature | |
7. | ALA3738524 | B | Inhibition of Staphylococcus aureus SecA1 assessed as reduction in secretion of enterotoxin B at 10 uM by Western blot analysis | Staphylococcus aureus | 1 | ALA3734668 | single protein format | Scientific Literature | |
8. | ALA3738525 | B | Inhibition of Staphylococcus aureus SecA1 assessed as reduction in secretion of TSST-1 at 10 uM by Western blot analysis | Staphylococcus aureus | 1 | ALA3734668 | single protein format | Scientific Literature |