# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3861044 | B | Inhibition of rat NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assay | Rattus norvegicus | 1 | ALA3860060 | cell-based format | Scientific Literature | |
2. | ALA3881393 | B | Inhibition of rat NHE3-mediated sodium-dependant hydrogen ion antiport in Opossum kidney cells preincubated in NH4Cl-HEPES buffer containing BCECF-AM dye followed by washout with ammonium free HEPES and subsequent addition of compound in presence of NHE1 antagonist EIPA by fluorescence assay | Rattus norvegicus | 179 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
3. | ALA3881403 | B | Inhibition of rat NHE3-mediated sodium-dependant hydrogen ion antiport in Opossum kidney cells preincubated for 60 mins in NaCl-HEPES buffer followed by compound washout with NH4Cl-HEPES buffer containing BCECF-AM dye and subsequent washout with Na+ free HEPES buffer by fluorescence analysis | Rattus norvegicus | 5 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
4. | ALA3881448 | B | Inhibition of rat NHE3 expressed in chinese hamster AP1 cells assessed as inhibition of acid-induced 22NA+ influx by liquid scintillation spectroscopy | Rattus norvegicus | 4 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
5. | ALA3881455 | B | Inhibition of rat NHE3 expressed in chinese hamster AP1 cells preincubated for 7.5 mins followed by addition of NaCl measured after 5 mins by BACEF-AM dye based fluorescence analysis | Rattus norvegicus | 1 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
6. | ALA3882136 | B | Inhibition of rat NHE-3-mediated Na+ dependent H+ antiport expressed in opossum kidney cells in presence of NHE-1 antagonist EIPA by BCECF-AM dye based fluorescence assay | Rattus norvegicus | 73 | ALA3881530 | cell-based format | Patent Bioactivity Data | |
7. | ALA3882219 | B | Inhibition of rat NHE-3 | Rattus norvegicus | 5 | ALA3881530 | single protein format | Patent Bioactivity Data | |
8. | ALA4257109 | B | Inhibition of rat NHE3 expressed in OK cells assessed as reduction in Na+ dependent H+ antiport in presence of NHE1 inhibitor EIPA by BCECF-AM dye based fluorescence assay | Rattus norvegicus | 182 | ALA4257082 | cell-based format | Patent Bioactivity Data | |
9. | ALA4257132 | B | Inhibition of rat NHE3 | Rattus norvegicus | 5 | ALA4257082 | single protein format | Patent Bioactivity Data | |
10. | ALA4257141 | B | Inhibition of rat NHE3 expressed in OK cells assessed as reduction in Na+ dependent H+ antiport co-treated with NaCl-HEPES buffer for 60 mins followed by compound washout and subsequent incubation for 30 mins in presence of NaCl-HEPES buffer by BCECF-AM dye based fluorescence assay | Rattus norvegicus | 5 | ALA4257082 | cell-based format | Patent Bioactivity Data | |
11. | ALA5149727 | B | Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ethyl isopropyl amiloride by BCECF-AM dye based fluorescence assay | Rattus norvegicus | 43 | ALA5143744 | cell-based format | Scientific Literature |