# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3862616 | B | Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentration by Fluo-4AM dye-based spectrofluorometry relative to ionomycin | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
2. | ALA3862617 | B | Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentration by Fluo-4AM dye-based spectrofluorometry | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
3. | ALA3862618 | B | Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincubated for 5 mins prior to thymol-stimulation by Fluo-4AM dye-based spectrofluorometry | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
4. | ALA4377086 | B | Inhibition of YFP-tagged rat TRPV3 expressed in HEK293 cells assessed as reduction in calcium level by fluo-4 dye based fluorescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
5. | ALA4478091 | B | Antagonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced intracellular calcium accumulation preincubated for 5 mins followed by thymol addition by Fluo-4-AM probe-based spectrofluorimetric assay | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
6. | ALA4478097 | B | Antagonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced intracellular calcium accumulation up to 10 uM preincubated for 5 mins followed by thymol addition by Fluo-4-AM probe-based spectrofluorimetric assay | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
7. | ALA4675873 | B | Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced Ca2+ response preincubated for 5 mins followed by thymol addition by Fluo-4AM dye based fluorescence assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
8. | ALA4675874 | B | Agonist activity at rat TRPV3 stably transfected in HEK293 cells assessed as increase in calcium influx in presence of ionomycin by Fluo-4-AM dye based spectrofluorimetric method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
9. | ALA4675875 | B | Agonist activity at rat TRPV3 stably transfected in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based spectrofluorimetric method relative to ionomycin | Rattus norvegicus | 2 | cell-based format | Scientific Literature |