# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3870140 | B | Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid measured after 6 hrs | Chlorocebus aethiops | 10 | ALA3868631 | cell-based format | Scientific Literature | |
2. | ALA3870145 | B | Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid at 10 ug/ml measured after 6 hrs relative to control | Chlorocebus aethiops | 13 | ALA3868631 | cell-based format | Scientific Literature | |
3. | ALA3882631 | B | Inhibition of African green monkey ACAT2 expressed in CHO cells assessed as reduction in [14C]CE formation using [1-14C]oleoyl-CoA measured after 6 hrs by TLC method | Chlorocebus aethiops | 2 | ALA3882390 | cell-based format | Patent Bioactivity Data | |
4. | ALA3882633 | B | Inhibition of African green monkey ACAT2 expressed in mouse AC29 cells assessed as reduction in esterification of NBD-cholesterol preincubated for 20 mins followed by NBD-cholesterol addition measured after 6 hrs by high-performance TLC method | Chlorocebus aethiops | 4 | ALA3882390 | cell-based format | Patent Bioactivity Data | |
5. | ALA4178542 | B | Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]oleic acid by thin-layer chromatography | Chlorocebus aethiops | 4 | ALA4177543 | cell-based format | Scientific Literature | |
6. | ALA4178544 | B | Inhibition of African green monkey SOAT2 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]oleoyl-CoA by thin-layer chromatography | Chlorocebus aethiops | 4 | ALA4177543 | assay format | Scientific Literature | |
7. | ALA4223480 | B | Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrs | Chlorocebus aethiops | 4 | ALA4219214 | cell-based format | Scientific Literature | |
8. | ALA4223483 | B | Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 mins | Chlorocebus aethiops | 4 | ALA4219214 | assay format | Scientific Literature | |
9. | ALA4349877 | B | Inhibition of African green monkey SOAT2 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based method | Chlorocebus aethiops | 2 | ALA4346732 | cell-based format | Scientific Literature | |
10. | ALA5243735 | B | Inhibition of african green monkey SAOT2 in CHO cells assessed as reduction cholesteryl ester synthesis | Chlorocebus aethiops | 4 | ALA5241121 | cell-based format | Scientific Literature |