# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3860462 | B | Induction of katanin p60 subunit-mediated JNK signaling pathway activation in human NCI-H1975 cells assessed as increase in JNK phosphorylation at T183/Y185 and T221/Y223 residues at 300 nM after 9 hrs by phospho-kinase antibody array method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA3860463 | B | Induction of katanin p60 subunit-mediated JNK signaling pathway activation in human NCI-H1975 cells assessed as increase in c-Jun phosphorylation at S63 residues at 300 nM after 9 hrs by phospho-kinase antibody array method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA3860464 | B | Induction of katanin p60 subunit-mediated JNK signaling pathway activation assessed as increase in phosphorylation level at T183/Y185 residues in human NCI-H1975 cells at 300 nM after 6 to 12 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA3860465 | B | Induction of katanin p60 subunit-mediated JNK signaling pathway activation assessed as increase in c-Jun phosphorylation level at S63 residues in human NCI-H1975 cells at 300 nM after 6 to 12 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA3860471 | B | Induction of katanin p60 subunit-mediated microtubule fragmentation in human NCI-H1975 cells at 300 nM after 12 hrs by DAPI staining based confocal laser microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA3860472 | B | Induction of katanin p60 subunit-mediated microtubule fragmentation in human NCI-H1975 cells assessed as alpha-tubulin level in soluble form at 300 nM after 1 hr by immunoblot analysis (Rvb = 37%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA3860473 | B | Induction of katanin p60 subunit-mediated microtubule fragmentation in human NCI-H1975 cells assessed as alpha-tubulin level in polymer form at 300 nM after 1 hr by immunoblot analysis (Rvb = 63%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA3860474 | B | Induction of katanin p60 subunit-mediated microtubule fragmentation in human NCI-H1975 cells assessed as alpha-tubulin level in soluble form at 600 nM after 1 hr by immunoblot analysis (Rvb = 37%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA3860475 | B | Induction of katanin p60 subunit-mediated microtubule fragmentation in human NCI-H1975 cells assessed as alpha-tubulin level in polymer form at 600 nM after 1 hr by immunoblot analysis (Rvb = 63%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA3860476 | B | Induction of katanin p60 subunit-mediated microtubule fragmentation in human NCI-H1975 cells assessed as alpha-tubulin level in soluble form at 300 nM after 12 hrs by gel filtration chromatography/immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA3860479 | B | Binding affinity to katanin p60 subunit in human NCI-H1975 cell lysate using biotin-labeled compound preincubated for 24 hrs followed by streptavidin-conjugated beads addition measured after 2 hrs by immunoblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA4360202 | B | Binding affinity to katanin p60 in human A549 cells incubated for 24 hrs and measured after 1 hr by streptavidin based pull down assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA4360205 | B | Inhibition of Katanin p60 degradation in human A549 cells preincubated for 15 mins followed by compound addition in presence of cycloheximide by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4362085 | B | Binding affinity to katanin p60 in human NCI-H1975 cells using biotin labelled compound incubated for 16 hrs by streptavidin based immunoprecipitation method | Homo sapiens | 3 | cell-based format | Scientific Literature |