# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3828959 | B | Inhibition of HDAC1/HDAC2 in mouse forebrain primary neuron assessed acetylation of H4K12 at 10 uM after 24 hrs by acumen microcytometric analysis | Mus musculus | 2 | assay format | Scientific Literature | ||
2. | ALA3828960 | B | Inhibition of HDAC1/HDAC2 in mouse forebrain primary neuron assessed acetylation of H3K9 at 10 uM after 24 hrs by acumen microcytometric analysis | Mus musculus | 2 | assay format | Scientific Literature | ||
3. | ALA4353993 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of TNF-alpha gene expression at 1 uM pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA4353994 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of IL-6 gene expression at 1 uM pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA4353995 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of iNOS gene expression at 1 uM pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA4353996 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of IL-10 gene expression at 1 uM pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA4353999 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of TNF-alpha gene expression at 1 to 5 uM pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
8. | ALA4354000 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of IL-6 gene expression at 1 to 5 uM pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
9. | ALA4354001 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of iNOS gene expression at 1 to 5 uM pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
10. | ALA4354002 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of IL-10 gene expression at 1 to 5 uM pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
11. | ALA4354007 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of TNF-alpha gene expression at pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
12. | ALA4354008 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of IL-6 gene expression at pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
13. | ALA4354009 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of iNOS gene expression at pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
14. | ALA4354010 | B | Inhibition of HDAC1/2 in LPS/IFNgamma-stimulated mouse RAW264.7 cells assessed as upregulation of IL-10 gene expression at pretreated for 16 hrs followed by LPS stimulation and measured after 4 hrs by RT-qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature |