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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3223538 | Binding | Inhibition of MDM2/MDMX-p53 interaction in human A2780 CP70 cells expressing p53 mutant gene assessed as induction of p21 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
2. | ALA3223539 | Binding | Inhibition of MDM2/MDMX-p53 interaction in human A2780 CP70 cells expressing p53 mutant gene assessed as induction of p53 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
3. | ALA3223540 | Binding | Inhibition of MDM2/MDMX-p53 interaction in human A2780 CP70 cells expressing p53 mutant gene assessed as induction of MDM2 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
4. | ALA3223541 | Binding | Inhibition of MDM2/MDMX-p53 interaction in human A2780 cells expressing wild-type p53 assessed as induction of p21 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
5. | ALA3223542 | Binding | Inhibition of MDM2/MDMX-p53 interaction in human A2780 cells expressing wild-type p53 assessed as induction of p53 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
6. | ALA3223543 | Binding | Inhibition of MDM2/MDMX-p53 interaction in human A2780 cells expressing wild-type p53 assessed as induction of MDM2 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
7. | ALA3223544 | Binding | Inhibition of MDM2/MDMX-p53 interaction in human SJSA-1 cells expressing amplified MDM2 and wild-type p53 assessed as induction of p21 protein expression at 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
8. | ALA3223545 | Binding | Inhibition of MDM2/MDMX-p53 interaction in human SJSA-1 cells expressing amplified MDM2 and wild-type p53 assessed as induction of p53 protein expression at 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
9. | ALA3223546 | Binding | Inhibition of MDM2/MDMX-p53 interaction in human SJSA-1 cells expressing amplified MDM2 and wild-type p53 assessed as induction of MDM2 protein expression at 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature |