# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3875506 | Binding | Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of MLL1 histone methyltransferase activity by measuring reduction in H3K4me1 level at 5 uM after 7 days by Western blot method | Homo sapiens | 1 | ALA3875159 | cell-based format | Scientific Literature | |
2. | ALA3875507 | Binding | Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of MLL1 histone methyltransferase activity by measuring reduction in H3K4me1 level at 10 uM after 7 days by Western blot method | Homo sapiens | 1 | ALA3875159 | cell-based format | Scientific Literature | |
3. | ALA3875508 | Binding | Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of MLL1 histone methyltransferase activity by measuring reduction in H3K4me2 level after 7 days by Western blot method | Homo sapiens | 1 | ALA3875159 | cell-based format | Scientific Literature | |
4. | ALA3875509 | Binding | Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of MLL1 histone methyltransferase activity by measuring reduction in H3K4me2 level at 10 uM after 7 days by Western blot method | Homo sapiens | 1 | ALA3875159 | cell-based format | Scientific Literature | |
5. | ALA3875510 | Binding | Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of Hoxa9 gene expression after 7 days by RT-PCR method | Homo sapiens | 1 | ALA3875159 | cell-based format | Scientific Literature | |
6. | ALA3875511 | Binding | Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of Meis-1 gene expression after 7 days by RT-PCR method | Homo sapiens | 1 | ALA3875159 | cell-based format | Scientific Literature | |
7. | ALA3875512 | Binding | Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of Hoxa9 gene expression at 2.5 uM after 7 days by RT-PCR method relative to control | Homo sapiens | 1 | ALA3875159 | cell-based format | Scientific Literature | |
8. | ALA3875513 | Binding | Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of Hoxa9 gene expression at 10 uM after 7 days by RT-PCR method relative to control | Homo sapiens | 1 | ALA3875159 | cell-based format | Scientific Literature | |
9. | ALA3875514 | Binding | Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of Meis-1 gene expression at 2.5 uM after 7 days by RT-PCR method relative to control | Homo sapiens | 1 | ALA3875159 | cell-based format | Scientific Literature | |
10. | ALA3875515 | Binding | Inhibition of MLL1-WDR5 protein-protein interaction in human MV4-11 cells harboring MLL-AF4 fusion protein assessed as inhibition of Meis-1 gene expression at 10 uM after 7 days by RT-PCR method relative to control | Homo sapiens | 1 | ALA3875159 | cell-based format | Scientific Literature | |
11. | ALA4186848 | Binding | Inhibition of MLL1-WDR5 (unknown origin) protein-protein interaction by fluorescence-labeled Ac-ARA peptide tracer based fluorescence polarization assay | Homo sapiens | 1 | ALA4184186 | protein format | Scientific Literature | |
12. | ALA4683551 | Binding | Inhibition of MLL1-WDR5 interaction in human MV4-11 cells assessed as downregulation of Hoxa9 gene expression incubated for 6 days by qRT-PCR analysis | Homo sapiens | 1 | ALA4680151 | cell-based format | Scientific Literature | |
13. | ALA4683552 | Binding | Inhibition of MLL1-WDR5 interaction in human MV4-11 cells assessed as downregulation of Meis1 gene expression incubated for 6 days by qRT-PCR analysis | Homo sapiens | 1 | ALA4680151 | cell-based format | Scientific Literature | |
14. | ALA4683553 | Binding | Inhibition of MLL1-WDR5 interaction in human MV4-11 cells assessed as downregulation of Hoxa9 gene expression at 5 uM incubated for 6 days by qRT-PCR analysis | Homo sapiens | 1 | ALA4680151 | cell-based format | Scientific Literature | |
15. | ALA4683554 | Binding | Inhibition of MLL1-WDR5 interaction in human MV4-11 cells assessed as downregulation of Meis1 gene expression at 5 uM incubated for 6 days by qRT-PCR analysis | Homo sapiens | 1 | ALA4680151 | cell-based format | Scientific Literature | |
16. | ALA4683555 | Binding | Inhibition of MLL1-WDR5 interaction in human MV4-11 cells assessed as reduction in H3K4me1 expression incubated for 6 days by Western blot analysis | Homo sapiens | 1 | ALA4680151 | cell-based format | Scientific Literature | |
17. | ALA4683556 | Binding | Inhibition of MLL1-WDR5 interaction in human MV4-11 cells assessed as reduction in H3K4me2 expression incubated for 6 days by Western blot analysis | Homo sapiens | 1 | ALA4680151 | cell-based format | Scientific Literature | |
18. | ALA4683557 | Binding | Inhibition of MLL1-WDR5 interaction in human MV4-11 cells assessed as reduction in H3K4me1 expression at 5 uM incubated for 6 days by Western blot analysis | Homo sapiens | 1 | ALA4680151 | cell-based format | Scientific Literature | |
19. | ALA4683558 | Binding | Inhibition of MLL1-WDR5 interaction in human MV4-11 cells assessed as reduction in H3K4me2 expression at 5 uM incubated for 6 days by Western blot analysis | Homo sapiens | 1 | ALA4680151 | cell-based format | Scientific Literature | |
20. | ALA4683559 | Binding | Inhibition of MLL1-WDR5 interaction in human MV4-11 cells assessed as reduction in MLL1 binding to WDR5 WIN site by 5-FAM probe based fluorescence polarization assay | Homo sapiens | 13 | ALA4680151 | cell-based format | Scientific Literature |