# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1050978 | Functional | Antagonist activity at nAChR-alpha-6-beta-2 in Sprague-Dawley rat striatal slices assessed as inhibition of nicotine-evoked [3H]dopamine uptake by liquid beta-scintillation spectrometry | Rattus norvegicus | 1 | ALA1153028 | assay format | Scientific Literature | |
2. | ALA1918979 | Functional | Agonist activity at rat alpha6beta2 nAChR assessed as [3H]dopamine release by beta counting | Rattus norvegicus | 1 | ALA1914327 | assay format | Scientific Literature | |
3. | ALA1918983 | Binding | Displacement of [3H]epibatidine from alpha6beta2 nAChR in Sprague-Dawley rat striatal slices by scintillation counting | Rattus norvegicus | 1 | ALA1914327 | protein complex format | Scientific Literature | |
4. | ALA1919175 | Functional | Partial agonist activity at rat alpha6beta2 nAChR in rat striatum containing other subunits of nAChR by beta counting in the presence of antagonist alphaconotoxin MII | Rattus norvegicus | 1 | ALA1914327 | tissue-based format | Scientific Literature | |
5. | ALA1919177 | Functional | Agonist activity at rat alpha6beta2 nAChR assessed as [3H]dopamine release from rat striatum by beta counting relative to 10 uM nicotine | Rattus norvegicus | 1 | ALA1914327 | assay format | Scientific Literature | |
6. | ALA1919178 | Functional | Partial agonist activity at alpha6beta2 nAChR in rat striatum assessed as decrease in [3H]dopamine release by beta counting in the presence of antagonist alphaconotoxin MII | Rattus norvegicus | 1 | ALA1914327 | tissue-based format | Scientific Literature | |
7. | ALA3615820 | Binding | Displacement of [3H]epibatidine from immunoimmobilized alpha6beta2 nAChR in Sprague-Dawley rat striatal membranes by liquid scintillation counting | Rattus norvegicus | 11 | ALA3611999 | assay format | Scientific Literature | |
8. | ALA3615824 | Binding | Ratio of NHNB Ki to compound Ki for immunoimmobilized alpha6beta2 nAChR in Sprague-Dawley rat striatal membranes | Rattus norvegicus | 3 | ALA3611999 | assay format | Scientific Literature |