# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3821983 | B | Competitive inhibition of wild type beta-catenin (unknown origin) expressed in Escherichia coli BL21 DE3 interaction with N-terminally biotinylated human BCL9 (350 to 375 residues) by alpha screen assay | Homo sapiens | 23 | assay format | Scientific Literature | ||
2. | ALA4419373 | B | Inhibition of C-terminal 6x-histidine tagged beta-catenin (138 to 686 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 /human BCL9 (350 to 375 residues) protein-protein interactions incubated for 1 hr by Alpha-screen assay | Homo sapiens | 57 | assay format | Patent Bioactivity Data | ||
3. | ALA4419380 | B | Inhibition of inhibited beta-catenin D145A mutant (unknown origin) expressed in Escherichia coli BL21 DE3 /human BCL9 (350 to 375 residues) protein-protein interactions by Alpha-screen assay | Homo sapiens | 3 | assay format | Patent Bioactivity Data | ||
4. | ALA4419381 | B | Inhibition of inhibited beta-catenin E155A mutant (unknown origin) expressed in Escherichia coli BL21 DE3 /human BCL9 (350 to 375 residues) protein-protein interactions by Alpha-screen assay | Homo sapiens | 3 | assay format | Patent Bioactivity Data | ||
5. | ALA4419382 | B | Inhibition of inhibited beta-catenin D145A/E155A mutant (unknown origin) expressed in Escherichia coli BL21 DE3 /human BCL9 (350 to 375 residues) protein-protein interactions by Alpha-screen assay | Homo sapiens | 3 | assay format | Patent Bioactivity Data | ||
6. | ALA4419401 | B | Inhibition of beta-catenin/BCL9 (unknown origin) expressed in Wnt-activated HEK293 cells assessed as reduction in canonical Wnt signaling transactivation by Wnt-responsive luciferase reporter assay | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
7. | ALA4419402 | B | Inhibition of beta-catenin/BCL9 in Wnt-activated human SW480 cells assessed as reduction in canonical Wnt signaling transactivation by Wnt-responsive luciferase reporter assay | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
8. | ALA4419403 | B | Inhibition of beta-catenin/BCL9 in Wnt-activated human MDA-MB-231 cells assessed as reduction in canonical Wnt signaling transactivation by Wnt-responsive luciferase reporter assay | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
9. | ALA4419404 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as Axin2 mRNA expression at 1 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
10. | ALA4419405 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as Axin2 mRNA expression at 2 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
11. | ALA4419406 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as Axin2 mRNA expression at 4 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
12. | ALA4419407 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as LGR5 mRNA expression at 1 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
13. | ALA4419408 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as LGR5 mRNA expression at 2 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
14. | ALA4419409 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as LGR5 mRNA expression at 4 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
15. | ALA4419410 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as LEF1 mRNA expression at 1 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
16. | ALA4419411 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as LEF1 mRNA expression at 2 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
17. | ALA4419412 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as LEF1 mRNA expression at 4 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
18. | ALA4419413 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as cyclin D1 mRNA expression at 1 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
19. | ALA4419414 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as cyclin D1 mRNA expression at 2 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
20. | ALA4419415 | B | Inhibition of beta-catenin/BCL9 in human MDA-MB-231 cells assessed as cyclin D1 mRNA expression at 4 uM by quantitative real-time PCR analysis based cell based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data |