# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2089705 | B | Inhibition of CDK4/CDK6 assessed as pRb phosphorylation in human JeKo1 cells by immunoblotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA5256381 | B | Inhibition of CDK4/CDK6 signaling pathway in human MDA-MB-231 cells assessed as reduction of RB phosphorylation at Ser780 residue level at 8 uM incubated for 24 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA5256382 | B | Inhibition of CDK4/CDK6 signaling pathway in human MDA-MB-231 cells assessed as inhibition of CDK6 expression level at 8 uM incubated for 24 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA5256383 | B | Inhibition of CDK4/CDK6 signaling pathway in human MDA-MB-231 cells assessed as inhibition of CDK4 expression level at 8 uM incubated for 24 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA5256384 | B | Inhibition of CDK4/CDK6 signaling pathway in human MDA-MB-231 cells assessed as reduction of RB phosphorylation at Ser780 residue level at 1 to 8 uM incubated for 24 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA5256385 | B | Inhibition of CDK4/CDK6 signaling pathway in human MDA-MB-231 cells assessed as inhibition of CDK6 expression level at 1 to 8 uM incubated for 24 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA5256386 | B | Inhibition of CDK4/CDK6 signaling pathway in human MDA-MB-231 cells assessed as inhibition of CDK4 expression level at 1 to 8 uM incubated for 24 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA3607001 | B | Inhibition of CDK4/6 in human COLO205 cells assessed as inhibition of Rb phosphorylation after 24 hrs by propidium iodide staining-based laser-scanning fluorescence microplate cytometric analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA3607002 | B | Inhibition of CDK4/6 in human COLO205 cells assessed as maximum cell cycle arrest at G1 phase after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
10. | ALA4005880 | B | Inhibition of CDK4/6 in human MV4-11 cells assessed as reduction in Rb phosphorylation at Ser780 after 12 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4005881 | B | Inhibition of CDK4/6 in human MV4-11 cells assessed as reduction in Rb phosphorylation at Ser780 at GI50 after 12 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4701434 | B | Inhibition of CDK4/6 in human MCF7 cells assessed as reduction in Rb phosphorylation at S807/811 residue incubated for 6 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4821691 | B | Inhibition of CDK4/6 in human MDA-MB-231 cells assessed as reduction in Rb phosphorylation at Ser780 after 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA5047211 | B | Inhibition of CDK4/CDK6 (unknown origin) at 1 uM in presence of 33P-ATP incubated for 2 hrs by kinase selectivity assay | Homo sapiens | 1 | protein format | Scientific Literature | ||
15. | ALA5047244 | B | Inhibition of CDK4/CDK6 in human RPMI-8226 cells assessed as reduction of p-RB level at 1.5 to 6 uM incubated for 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |