# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3880022 | B | Activation of TRPM5 in mouse GLUTag cells assessed as induction of 0.1 mM glucose-mediated GLP-1 secretion at 0.1 uM to 10 M after 2 hrs by ELISA | Mus musculus | 1 | ALA3879891 | cell-based format | Patent Bioactivity Data | |
2. | ALA3880023 | B | Activation of TRPM5 in mouse GLUTag cells assessed as induction of 0.3 mM glucose-mediated GLP-1 secretion after 2 hrs by ELISA | Mus musculus | 1 | ALA3879891 | cell-based format | Patent Bioactivity Data | |
3. | ALA3880026 | B | Activation of TRPM5 in SV40 expressing transgenic mouse Beta-TC-6 cells assessed as induction of 0.3 mM glucose-mediated insulin secretion at 0.03 to 3 uM after 2 hrs by ELISA | Mus musculus | 1 | ALA3879891 | assay format | Patent Bioactivity Data | |
4. | ALA3880027 | B | Activation of TRPM5 in SV40 expressing transgenic mouse Beta-TC-6 cells assessed as induction of 1 mM glucose-mediated insulin secretion after 2 hrs by ELISA | Mus musculus | 1 | ALA3879891 | assay format | Patent Bioactivity Data | |
5. | ALA4824107 | B | Agonist activity at mouse TRPM5 expressed in CHO-K1 cells maintained at 80 mV final holding potential by syncroPatch assay | Mus musculus | 4 | ALA4823260 | cell-based format | Scientific Literature | |
6. | ALA5153256 | B | Agonist activity at mouse TRPM5 expressed in CHO-K1 cells | Mus musculus | 1 | ALA5150049 | cell-based format | Scientific Literature | |
7. | ALA5153274 | B | Binding affinity to mouse colon mucosal epithelium TRPM5 assessed as increase in short circuit current | Mus musculus | 1 | ALA5150049 | tissue-based format | Scientific Literature |