| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1920845 | B | Induction of ribosome to readthrough in human A-T lymphoblastoid cells assessed as ATM ser1981 autophosphorylation at 30 uM after 4 days by PTT-ELISA assay | Homo sapiens | 41 | subcellular format | Scientific Literature | ||
| 2. | ALA1920846 | B | Induction of ribosome to readthrough in human A-T lymphoblastoid cells assessed as irradiation-induced ATM Ser1981 nuclear foci formation at 30 uM after 4 days by PTT-ELISA | Homo sapiens | 13 | subcellular format | Scientific Literature | ||
| 3. | ALA2214721 | B | Inhibition of ribosome-mediated translation of CFTR W1282X nonsense mutant gene expressed in human HEK293 cells after 16 hrs by dual luciferase reporter gene assay | Homo sapiens | 5 | subcellular format | Scientific Literature | ||
| 4. | ALA2214722 | B | Inhibition of mitochondrial ribosome-mediated protein synthesis in human HeLa cells assessed as {35S]methionine incorporation by autoradiography | Homo sapiens | 16 | subcellular format | Scientific Literature | ||
| 5. | ALA2215168 | B | Inhibition of ribosome-mediated translation of PCDH15 R245X nonsense mutant gene expressed in human HEK293 cells after 16 hrs by dual luciferase reporter gene assay | Homo sapiens | 5 | subcellular format | Scientific Literature | ||
| 6. | ALA2215169 | B | Inhibition of ribosome-mediated translation of PCDH15 R3X nonsense mutant gene expressed in human HEK293 cells after 16 hrs by dual luciferase reporter gene assay | Homo sapiens | 5 | subcellular format | Scientific Literature | ||
| 7. | ALA2215170 | B | Inhibition of ribosome-mediated translation of CFTR WG542X nonsense mutant gene expressed in human HEK293 cells after 16 hrs by dual luciferase reporter gene assay | Homo sapiens | 5 | subcellular format | Scientific Literature | ||
| 8. | ALA3224167 | B | Induction of ribosome-mediated readthrough activity in R3X-transfected HEK293 cells assessed as suppression of R3X mutation after 16 hrs by dual luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA3224168 | B | Induction of ribosome-mediated readthrough activity in R245X-transfected HEK293 cells assessed as suppression of R245X mutation after 16 hrs by dual luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA3224169 | B | Induction of ribosome-mediated readthrough activity in Q70X-transfected HEK293 cells assessed as suppression of Q70X mutation after 16 hrs by dual luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA3224170 | B | Induction of ribosome-mediated readthrough activity in W1282X-transfected HEK293 cells assessed as suppression of W1282X mutation after 16 hrs by dual luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA3591840 | B | Inhibition of human ribosome containing eukaryotic wild type ribosomal RNA A-site in rabbit reticulocyte lysates assessed as reduction in ribosome-mediated protein synthesis in presence of S-30 extracts by fire fly luciferase synthesis based cell-free translation assay | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 13. | ALA4118561 | B | Binding affinity to RPS25 in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4118577 | B | Binding affinity to RPL8 in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4118586 | B | Binding affinity to RPL27 in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4118589 | B | Binding affinity to RPL23A in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4118593 | B | Binding affinity to RPS26 in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4118595 | B | Binding affinity to RPS5 in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4118611 | B | Binding affinity to RPLP1 in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4118658 | B | Binding affinity to RPL28 in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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