#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4031179	B	Binding affinity to human cGAS (2 to 522 residues) expressed in Sf9 insect cells by surface plasmon resonance assay	Homo sapiens	6	ALA4028860	cell-based format	Scientific Literature
2.	ALA4031180	B	Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presence of ATP and GTP after 30 mins by mass spectrometric analysis	Homo sapiens	6	ALA4028860	cell-based format	Scientific Literature
3.	ALA4031181	B	Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presence of ATP and GTP incubated for 1 hr followed by Cy5-labeled cGAMP addition measured after 1 hr by fluorescence polarization assay	Homo sapiens	6	ALA4028860	cell-based format	Scientific Literature
4.	ALA4031182	B	Inhibition of cGAS in human THP1 cells assessed as reduction in salmon sperm dsDNA-induced IFN-beta expression preincubated for 1 hr followed by dsDNA stimulation for 12 hrs by luciferase reporter gene assay	Homo sapiens	5	ALA4028860	cell-based format	Scientific Literature
5.	ALA4338389	A	Substrate activity at recombinant full-length human CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of GTP by HPLC-UV analysis	Homo sapiens	41	ALA4334523	assay format	Scientific Literature
6.	ALA4338392	A	Substrate activity at recombinant full-length human CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of ATP by HPLC-UV analysis	Homo sapiens	41	ALA4334523	assay format	Scientific Literature
7.	ALA4373751	B	Binding affinity to human CGAS after 1 hr in presence of Cy5-labeled cGAMP by fluorescence polarization assay	Homo sapiens	1	ALA4373628	single protein format	Scientific Literature
8.	ALA4373755	B	Inhibition of human CGAS after 7 hrs by RF-MS analysis	Homo sapiens	1	ALA4373628	single protein format	Scientific Literature
9.	ALA4373771	B	Binding affinity to STING (unknown origin)	Homo sapiens	1	ALA4373628	single protein format	Scientific Literature
10.	ALA4418453	B	Inhibition of recombinant His6-SUMO tagged human CGAS expressed in Escherichia coli BL21/pLys cells incubated for 20 mins by Kinase Glo chemiluminescence assay	Homo sapiens	298	ALA4418308	cell-based format	Patent Bioactivity Data
11.	ALA4418454	B	Inhibition of CGAS in human THP1 cells transfected with interferon stimulatory DNA and measured after 16 hrs by Gaussia luciferase reporter gene assay	Homo sapiens	99	ALA4418308	cell-based format	Patent Bioactivity Data
12.	ALA4418455	B	Inhibition of CGAS in human THP1 cells transfected with mock Sendai virus and measured after 16 hrs by Gaussia luciferase reporter gene assay	Homo sapiens	99	ALA4418308	cell-based format	Patent Bioactivity Data
13.	ALA4433342	B	Binding affinity to human Cyclic GMP-AMP synthase (2 to 522 residues) expressed in Sf9 cells by surface plasmon resonance analysis	Homo sapiens	2	ALA4433198	cell-based format	Scientific Literature
14.	ALA5040020	B	Inhibition of human cGAS expressed in THP1-Dual cells transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced activation of cGAS incubated for 1 hr by Quanti-luc reagent based assay	Homo sapiens	47	ALA5038595	cell-based format	Scientific Literature
15.	ALA5040027	B	Binding affinity to human cGAS in THP-1-Dual cells assessed as thermal stabilization by measuring denaturation temperature at 25 uM incubated for 1 hr by cellular thermal shift assay	Homo sapiens	1	ALA5038595	cell-based format	Scientific Literature
16.	ALA5040028	B	Inhibition of ds-DNA induced cGAS activation in human THP-1-Dual cells assessed as reduction in ds-DNA induced IRF luciferase signal incubated for 1 hr by Quanti-luc reagent based assay	Homo sapiens	1	ALA5038595	cell-based format	Scientific Literature
17.	ALA5040035	B	Inhibition of human cGAS incubated for 1 hr followed by Cy5-labeled cGAMP addition and measured after 1 hr by fluorescence polarization assay	Homo sapiens	1	ALA5038595	single protein format	Scientific Literature
18.	ALA5040036	B	Binding affinity to human cGAS assessed as dissociation constant	Homo sapiens	1	ALA5038595	single protein format	Scientific Literature
19.	ALA5040037	B	Inhibition of human cGAS assessed as reduction in 2,3-cGAMP synthesis by measuring ATP consumption incubated for 20 mins by Kinase Glo luminescence assay	Homo sapiens	1	ALA5038595	single protein format	Scientific Literature
20.	ALA5040038	B	Inhibition of human cGAS	Homo sapiens	4	ALA5038595	single protein format	Scientific Literature