# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4009307 | B | Activation of BTN3A1 in human Vgamma9Vdelta2 T cells assessed as induction of interleukin 2 stimulated cell proliferation by measuring increase in CD3 positive cells at 0.1 uM treated for 72 hrs measured on day 11 post last treatment by flow cytometry | Homo sapiens | 3 | ALA4007426 | cell-based format | Scientific Literature | |
2. | ALA4009308 | B | Activation of BTN3A1 in human Vgamma9Vdelta2 T cells assessed as induction of interleukin 2 stimulated cell proliferation by measuring increase in gammadelta T cell receptor positive cells at 0.1 uM treated for 72 hrs measured on day 11 post last treatment by flow cytometry | Homo sapiens | 3 | ALA4007426 | assay format | Scientific Literature | |
3. | ALA4009309 | B | Activation of BTN3A1 in human Vgamma9Vdelta2 T cells assessed as induction of interleukin 2 stimulated cell proliferation treated for 72 hrs measured on day 11 post last treatment by flow cytometry | Homo sapiens | 8 | ALA4007426 | assay format | Scientific Literature | |
4. | ALA4009310 | B | Potency index, ratio of HMBPP EC50 to compound EC50 for BTN3A1 in human Vgamma9Vdelta2 T cells | Homo sapiens | 7 | ALA4007426 | assay format | Scientific Literature | |
5. | ALA4009313 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
6. | ALA4009314 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in enthalpy at 240 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
7. | ALA4009315 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in enthalpy at 480 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
8. | ALA4009316 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in enthalpy at 688 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
9. | ALA4009317 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in entropy at 240 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
10. | ALA4009318 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in entropy at 480 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
11. | ALA4009319 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in entropy at 688 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
12. | ALA4009320 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as Gibbs free energy change at 240 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
13. | ALA4009321 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as Gibbs free energy change at 480 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
14. | ALA4009322 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as Gibbs free energy change at 688 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
15. | ALA4009323 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) at 240 to 860 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
16. | ALA4009324 | B | Inhibition of HMBPP binding to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in enthalpy of HMBPP binding at 10-fold higher dose of compound by isothermal titration calorimetry (Rvb = -52 kJ/mol) | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
17. | ALA4009325 | B | Inhibition of HMBPP binding to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in entropy of HMBPP binding at 10-fold higher dose of compound by isothermal titration calorimetry (Rvb = 19 kJ/mol) | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
18. | ALA4009326 | B | Inhibition of HMBPP binding to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in enthalpy of HMBPP binding at 100-fold molar excess of compound by isothermal titration calorimetry (Rvb = -52 kJ/mol) | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
19. | ALA4009327 | B | Inhibition of HMBPP binding to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in entropy of HMBPP binding at 100-fold molar excess of compound by isothermal titration calorimetry (Rvb = 19 kJ/mol) | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature | |
20. | ALA4009328 | B | Inhibition of HMBPP binding to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) by isothermal titration calorimetry | Homo sapiens | 1 | ALA4007426 | cell-based format | Scientific Literature |