| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4009307 | B | Activation of BTN3A1 in human Vgamma9Vdelta2 T cells assessed as induction of interleukin 2 stimulated cell proliferation by measuring increase in CD3 positive cells at 0.1 uM treated for 72 hrs measured on day 11 post last treatment by flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4009308 | B | Activation of BTN3A1 in human Vgamma9Vdelta2 T cells assessed as induction of interleukin 2 stimulated cell proliferation by measuring increase in gammadelta T cell receptor positive cells at 0.1 uM treated for 72 hrs measured on day 11 post last treatment by flow cytometry | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 3. | ALA4009309 | B | Activation of BTN3A1 in human Vgamma9Vdelta2 T cells assessed as induction of interleukin 2 stimulated cell proliferation treated for 72 hrs measured on day 11 post last treatment by flow cytometry | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 4. | ALA4009310 | B | Potency index, ratio of HMBPP EC50 to compound EC50 for BTN3A1 in human Vgamma9Vdelta2 T cells | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 5. | ALA4009313 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4009314 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in enthalpy at 240 uM by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4009315 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in enthalpy at 480 uM by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4009316 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in enthalpy at 688 uM by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4009317 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in entropy at 240 uM by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4009318 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in entropy at 480 uM by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4009319 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in entropy at 688 uM by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4009320 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as Gibbs free energy change at 240 uM by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4009321 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as Gibbs free energy change at 480 uM by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4009322 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as Gibbs free energy change at 688 uM by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4009323 | B | Binding affinity to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) at 240 to 860 uM by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4009324 | B | Inhibition of HMBPP binding to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in enthalpy of HMBPP binding at 10-fold higher dose of compound by isothermal titration calorimetry (Rvb = -52 kJ/mol) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4009325 | B | Inhibition of HMBPP binding to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in entropy of HMBPP binding at 10-fold higher dose of compound by isothermal titration calorimetry (Rvb = 19 kJ/mol) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4009326 | B | Inhibition of HMBPP binding to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in enthalpy of HMBPP binding at 100-fold molar excess of compound by isothermal titration calorimetry (Rvb = -52 kJ/mol) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4009327 | B | Inhibition of HMBPP binding to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) assessed as change in entropy of HMBPP binding at 100-fold molar excess of compound by isothermal titration calorimetry (Rvb = 19 kJ/mol) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4009328 | B | Inhibition of HMBPP binding to recombinant C-terminal His-tagged BTN3A1 intracellular domain (unknown origin) expressed in BL21(DE) by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature |
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