# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4015777 | B | Inhibition of SMRT peptide binding to 15N-labeled human BCL6 BTB domain C8Q/C67R/C84N mutant expressed in Escherichia coli BL21 by 2D-NMR method | Homo sapiens | 1 | ALA4014321 | assay format | Scientific Literature | |
2. | ALA4015778 | B | Inhibition of SMRT2 H1426W mutant peptide binding to N-terminal His6-tagged human BCL6 BTB domain C8Q/C67R/C84N mutant expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by SMRT2 H1426W mutant peptide addition measured after 60 mins by time-resolved fluorescence resonance energy transfer assay | Homo sapiens | 36 | ALA4014321 | assay format | Scientific Literature | |
3. | ALA4015779 | B | Binding affinity to N-terminal His6-tagged human BCL6 BTB domain C8Q/C67R/C84N mutant expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance spectrometry | Homo sapiens | 10 | ALA4014321 | assay format | Scientific Literature | |
4. | ALA4015780 | B | Binding affinity to N-terminal His6-tagged human BCL6 BTB domain C8Q/C67R/C84N mutant expressed in Escherichia coli BL21 (DE3) assessed as association rate constant by surface plasmon resonance spectrometry | Homo sapiens | 7 | ALA4014321 | assay format | Scientific Literature | |
5. | ALA4015781 | B | Binding affinity to N-terminal His6-tagged human BCL6 BTB domain C8Q/C67R/C84N mutant expressed in Escherichia coli BL21 (DE3) assessed as dissociation rate constant by surface plasmon resonance spectrometry | Homo sapiens | 7 | ALA4014321 | assay format | Scientific Literature | |
6. | ALA4015787 | B | Inhibition of GAL4 DNA binding domain fused BCL6 BTB domain (unknown origin) expressed in HEK 293T/17 cells after 24 hrs by Bright-Glo luciferase cell reporter assay | Homo sapiens | 18 | ALA4014321 | cell-based format | Scientific Literature | |
7. | ALA4028445 | B | Displacement of A633-labeled SMRT-BBD peptide from human BCL6 BTB domain expressed in Escherichia coli by fluorescence polarization assay | Homo sapiens | 1 | ALA4024797 | assay format | Scientific Literature | |
8. | ALA4044890 | B | Binding affinity to wild-type avi-tagged BCL6 BTB domain (unknown origin) by SPR analysis | Homo sapiens | 2 | ALA4043133 | single protein format | Scientific Literature | |
9. | ALA4044902 | B | Binding affinity to recombinant RED-NHS labelled BCL6 BTB domain (1 to 129 residues) (unknown origin) after 10 mins by microscale thermophoresis method | Homo sapiens | 2 | ALA4043133 | single protein format | Scientific Literature | |
10. | ALA4044903 | B | Displacement of A488-SMRT from BCL6 BTB domain (unknown origin) by fluorescence polarization assay | Homo sapiens | 1 | ALA4043133 | single protein format | Scientific Literature | |
11. | ALA4044904 | B | Inhibition of C-terminal biotin-labelled BCoR (Arg498 to 514Pro residues) binding to recombinant FLAG-tagged BCL6 BTB (5 to 129 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) by ELISA | Homo sapiens | 1 | ALA4043133 | assay format | Scientific Literature | |
12. | ALA4044905 | B | Binding affinity to biotinylated BCL6 (unknown origin) by SPR analysis | Homo sapiens | 1 | ALA4043133 | single protein format | Scientific Literature | |
13. | ALA4052313 | B | Binding affinity to captured wild-type human biotinylated Avi-tagged BCL6 BTB domain (5 to 129 amino acid residues) expressed in Escherichia coli BL21 (DE3) by SPR analysis | Homo sapiens | 8 | ALA4049455 | assay format | Scientific Literature | |
14. | ALA4052314 | B | Binding affinity to captured human biotinylated Avi-tagged BCL6 BTB domain (5 to 129 amino acid residues) C8Q/C67R/C84N triple mutant expressed in Escherichia coli BL21 (DE3) by SPR analysis | Homo sapiens | 1 | ALA4049455 | assay format | Scientific Literature | |
15. | ALA4052315 | B | Binding affinity to coupled wild-type human biotinylated Avi-tagged BCL6 BTB domain (5 to 129 amino acid residues) expressed in Escherichia coli BL21 (DE3) by SPR analysis | Homo sapiens | 1 | ALA4049455 | assay format | Scientific Literature | |
16. | ALA4052316 | B | Binding affinity to wild-type human biotinylated Avi-tagged BCL6 BTB domain (5 to 129 amino acid residues) expressed in Escherichia coli BL21 (DE3) using 1 % DMSO by SPR analysis | Homo sapiens | 1 | ALA4049455 | assay format | Scientific Literature | |
17. | ALA4052317 | B | Binding affinity to wild-type human biotinylated Avi-tagged BCL6 BTB domain (5 to 129 amino acid residues) expressed in Escherichia coli BL21 (DE3) using 3 % DMSO by SPR analysis | Homo sapiens | 1 | ALA4049455 | assay format | Scientific Literature | |
18. | ALA4052318 | B | Binding affinity to wild-type human biotinylated Avi-tagged BCL6 BTB domain (5 to 129 amino acid residues) expressed in Escherichia coli BL21 (DE3) using 5 % DMSO by SPR analysis | Homo sapiens | 1 | ALA4049455 | assay format | Scientific Literature | |
19. | ALA4052319 | B | Binding affinity to human biotinylated Avi-tagged BCL6 BTB domain C8Q/C67R/C84N triple mutant expressed in Escherichia coli BL21 (DE3) using 1 % DMSO by SPR analysis | Homo sapiens | 1 | ALA4049455 | assay format | Scientific Literature | |
20. | ALA4052320 | B | Binding affinity to human biotinylated Avi-tagged BCL6 BTB domain C8Q/C67R/C84N triple mutant expressed in Escherichia coli BL21 (DE3) using 3 % DMSO by SPR analysis | Homo sapiens | 1 | ALA4049455 | assay format | Scientific Literature |