# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4034894 | B | Agonist activity at mouse GPR52 | Mus musculus | 1 | ALA4033652 | single protein format | Scientific Literature | |
2. | ALA4034895 | B | Agonist activity at mouse GPR52 relative to (N-(2-hydroxyethyl)-3-(2-(3-(trifluoromethyl)benzyl)-1-benzofuran-4-yl)benzamide) | Mus musculus | 1 | ALA4033652 | single protein format | Scientific Literature | |
3. | ALA4711942 | B | Antagonist activity at GPR52 in mouse STHdhQ7/111 cells assessed as decrease in mHTT levels incubated for 48 hrs in presence of 2B7-terbium and 2166-D2 antibodies by TR-FRET | Mus musculus | 1 | ALA4706623 | cell-based format | Scientific Literature | |
4. | ALA4711943 | B | Antagonist activity at GPR52 in mouse STHdhQ7/111 cells assessed as decrease in mHTT levels at 1 to 10 uM incubated for 48 hrs in presence of 2B7-terbium and 2166-D2 antibodies by western blot analysis | Mus musculus | 1 | ALA4706623 | cell-based format | Scientific Literature | |
5. | ALA4711944 | B | Antagonist activity at GPR52 in mouse STHdhQ7/111 cells assessed as decrease in wild type HTT levels at 1 to 10 uM incubated for 48 hrs in presence of 2B7-terbium and 2166-D2 antibodies by western blot analysis | Mus musculus | 1 | ALA4706623 | cell-based format | Scientific Literature | |
6. | ALA4711947 | B | Antagonist activity at GPR52 in neurons from HdhQ7/Q140 mouse assessed as decrease in mHTT levels at 0.1 to 3 uM incubated for 48 hrs in presence of 2B7-terbium and 2166-D2 antibodies by TR-FRET analysis | Mus musculus | 1 | ALA4706623 | tissue-based format | Scientific Literature | |
7. | ALA4711948 | B | Antagonist activity at GPR52 in neurons from HdhQ7/Q140 mouse assessed as decrease in wild type HTT levels at 0.1 to 3 uM incubated for 48 hrs in presence of 2B7-terbium and 2166-D2 antibodies by TR-FRET analysis | Mus musculus | 1 | ALA4706623 | tissue-based format | Scientific Literature | |
8. | ALA4711949 | B | Antagonist activity at GPR52 in neurons from HdhQ7/Q140 mouse assessed as decrease in mHTT levels at 0.3 to 3 uM incubated for 48 hrs in presence of 2B7-terbium and 2166-D2 antibodies by western blot analysis | Mus musculus | 1 | ALA4706623 | tissue-based format | Scientific Literature | |
9. | ALA4711950 | B | Antagonist activity at GPR52 in neurons from HdhQ7/Q140 mouse assessed as decrease in wild type HTT levels at 0.3 to 3 uM incubated for 48 hrs in presence of 2B7-terbium and 2166-D2 antibodies by western blot analysis | Mus musculus | 1 | ALA4706623 | tissue-based format | Scientific Literature | |
10. | ALA4806972 | F | In vivo agonist activity at GPR52 in po dosed C57BL/6 mouse assessed as inhibition of basal locomotor activity measured for 60 mins starting at 15 mins post-drug challenge | Mus musculus | 1 | ALA4806956 | organism-based format | Patent Bioactivity Data | |
11. | ALA4806973 | F | In vivo agonist activity at GPR52 in C57BL/6 mouse assessed as inhibition of basal locomotor activity at 10 mg/kg, po measured for 60 mins starting at 15 mins post-drug challenge | Mus musculus | 13 | ALA4806956 | organism-based format | Patent Bioactivity Data | |
12. | ALA4883191 | F | CHO-based cAMP assay (mouse) | Mus musculus | 1 | ALA4507305 | assay format | Donated Chemical Probes - SGC Frankfurt |