| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4015194 | B | Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in membrane depolarization measured for 2.5 mins in presence of 2 mM Ca2+ by FLIPR membrane potential dye-based fluorescence assay | Homo sapiens | 1 | ALA4014306 | cell-based format | Scientific Literature | |
| 2. | ALA4015195 | B | Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 mM Ca2+ by Fluo8-AM dye-based fluorescence assay | Homo sapiens | 4 | ALA4014306 | cell-based format | Scientific Literature | |
| 3. | ALA4015214 | B | Agonist activity at human TRPC7 receptor expressed in HEK293 cells assessed as induction of channel current in presence of 0.1 mM Ca2+ by whole cell patch-clamp method | Homo sapiens | 1 | ALA4014306 | cell-based format | Scientific Literature | |
| 4. | ALA4015215 | B | Antagonist activity at human TRPC7 receptor expressed in HEK293 cells assessed as channel desensitization up to 30 uM in presence of 0.1 mM Ca2+ by whole cell patch-clamp method | Homo sapiens | 1 | ALA4014306 | cell-based format | Scientific Literature | |
| 5. | ALA4377109 | B | Inhibition of human TRPC7 expressed in HEK293 cells assessed as reduction in OAG-induced calcium influx after 10 mins by fluo-4/AM dye based FLIPR assay | Homo sapiens | 1 | ALA4376804 | cell-based format | Scientific Literature | |
| 6. | ALA4411002 | B | Inhibition of TRPC7 channel (unknown origin) | Homo sapiens | 1 | ALA4406916 | single protein format | Scientific Literature | |
| 7. | ALA4714761 | B | Inhibition of human TRPC7 expressed in HEK293 cells assessed as inhibition of GSK170-induced current at 10 uM by whole cell patch-clamp method | Homo sapiens | 1 | ALA4706728 | cell-based format | Scientific Literature | |
| 8. | ALA5145642 | B | Inhibition of TRPC7 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of GSK1702934A-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA5143583 | cell-based format | Scientific Literature |
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