| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4016793 | B | Stimulation of rat recombinant sGCalpha1 subunit expressed in CHO cells using alpha-[32P]GTP as substrate assessed as >=3 fold increase in [32P]cGMP formation after 10 mins by radioimmunoassay | Rattus norvegicus | 24 | cell-based format | Scientific Literature | ||
| 2. | ALA4809275 | B | Activation of recombinant rat sGC alpha1 subunit expressed in CHO cells assessed as induction of [32P-cGMP] formation using alpha-[32P-GTP] as substrate measured after 6 mins by luminescence assay | Rattus norvegicus | 40 | cell-based format | Scientific Literature | ||
| 3. | ALA4809276 | B | Activation of recombinant rat sGC alpha1 subunit expressed in CHO cells assessed as induction of [32P-cGMP] formation by measuring efficacy using alpha-[32P-GTP] as substrate measured after 6 mins by luminescence assay relative to control | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
| 4. | ALA4809308 | B | Activation of recombinant rat sGC alpha1 subunit expressed in CHO cells assessed as induction of [32P-cGMP] formation by measuring fold change at 0.01 uM using alpha-[32P-GTP] as substrate measured after 6 mins by luminescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4809309 | B | Activation of recombinant rat sGC alpha1 subunit expressed in CHO cells assessed as induction of [32P-cGMP] formation by measuring fold change at 100 uM using alpha-[32P-GTP] as substrate measured after 6 mins by luminescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4809310 | B | Activation of recombinant rat sGC alpha1 subunit expressed in CHO cells assessed as induction of [32P-cGMP] formation at 0.01 to 100 uM using alpha-[32P-GTP] as substrate measured after 6 mins in presence of NO by luminescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4809311 | B | Activation of recombinant rat sGC alpha1 subunit expressed in CHO cells assessed as induction of [32P-cGMP] formation at 0.01 to 100 uM using alpha-[32P-GTP] as substrate measured after 6 mins in presence of ODQ by luminescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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