| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3994501 | B | Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition to induce Bim protein expression measured after 24 hrs by Cell Titer-Glo assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
| 2. | ALA3994504 | B | Inhibition of SDHB in human U2OS cells over-expressing tBid assessed as reduction in apoptosis preincubated for 1 hr followed by doxycyclin addition to induce tBid protein expression measured after 24 hrs by Cell Titer-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3994508 | B | Irreversible inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by compound washout and doxycyclin addition to induce Bim protein expression measured after 24 hrs by Cell Titer-Glo assay | Homo sapiens | 12 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!