# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA859805 | B | Inhibitory activity against Hsp90 in human breast cancer SKBr3 cell line | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
2. | ALA859806 | F | Inhibition of Her2 degradation in human breast cancer SKBr3 cell line | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
3. | ALA859807 | B | Inhibitory activity against Hsp90 in human breast cancer MDA-MB-468 cell line | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
4. | ALA859861 | F | Binding affinity to Hsp90 in lung tissue | 3 | assay format | Scientific Literature | |||
5. | ALA859862 | F | Binding affinity to Hsp90 in heart tissue | 3 | tissue-based format | Scientific Literature | |||
6. | ALA859863 | F | Specificity towards transformed SKBr3 cell line over normal lung tissue Hsp90 | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA858772 | F | Specificity towards transformed SKBr3 cell line over normal heart tissue Hsp90 | Homo sapiens | 3 | tissue-based format | Scientific Literature | ||
8. | ALA2044533 | B | Displacement of [3H]17AAG from human recombinant Hsp90 after 30 mins by beta scintillation counting | Homo sapiens | 63 | single protein format | Scientific Literature | ||
9. | ALA2044538 | B | Inhibition of Hsp90 in human A2780 cells assessed as Hsp70 upregulation after 24 hrs by immunostaining method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA2065545 | B | Inhibition of HSP90 in human MCF7 cells assessed as degradation of Raf1 protein after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA2065546 | B | Inhibition of HSP90 in human MCF7 cells assessed as degradation of Akt protein after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA1832712 | B | Binding affinity to HSP90 | 1 | single protein format | Scientific Literature | |||
13. | ALA1918874 | B | Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
14. | ALA1918875 | B | Inhibition of human Hsp90beta after overnight incubation by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA1918878 | B | Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
16. | ALA1918879 | B | Binding affinity to human Hsp90beta assessed as association constant after overnight incubation by fluorescence polarization assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
17. | ALA1919072 | B | Binding affinity to human Hsp90beta assessed as dissociation constant after overnight incubation by fluorescence polarization assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
18. | ALA1925802 | B | Inhibition of human C-terminal domain of Hsp90 in MCF7 cells assessed as Her2 degradation at 0.1 to 100 uM by Western blotting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA1925803 | B | Inhibition of human C-terminal domain of Hsp90 in MCF7 cells assessed as Raf degradation at 0.1 to 100 uM by Western blotting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA1925804 | B | Inhibition of human C-terminal domain of Hsp90 in MCF7 cells assessed as Akt degradation at 0.1 to 100 uM by Western blotting | Homo sapiens | 2 | cell-based format | Scientific Literature |