# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5251993 | B | Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | single protein format | Scientific Literature | ||
2. | ALA5252005 | B | Binding affinity to sigma 2 receptor in human MCF7 cells assessed as increase in fluorescent intensity pretreated with (+)-pentazocine for 60 mins followed by compound addition incubated for 45 mins by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA5252007 | B | Binding affinity to sigma 2 receptor in human MCF7 cells assessed as displacement of compound by measuring inhibition constant of DTG incubated for 120 mins by saturation binding assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA5252008 | B | Binding affinity to sigma 2 receptor in human MCF7 cells assessed as displacement of compound by measuring inhibition constant of 2-(3-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)propyl)-5-methoxy-3,4-dihydroisoquinolin-1(2H)-one incubated for 120 mins by saturation binding assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA5250275 | B | Displacement of [3H]DTG from sigma-2 receptor in HEK293 cell membrane assessed as inhibition constant | Homo sapiens | 20 | cell membrane format | Scientific Literature | ||
6. | ALA4022868 | B | Displacement of [3H]-DTG from sigma 2 receptor (unknown origin) after 120 mins by liquid scintillation counting method | Homo sapiens | 9 | single protein format | Scientific Literature | ||
7. | ALA4039179 | B | Inhibition of sigma2 receptor (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA4050673 | B | Antagonist activity at sigma2 receptor (unknown origin) at 25 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA4131892 | B | Displacement of [3H]-DTG from S2R in human Jurkat cell membranes after 1 hr in presence of (+)-pentazocine by liquid scintillation counting | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
10. | ALA4148656 | B | Binding affinity to sigma-2 receptor (unknown origin) | Homo sapiens | 8 | single protein format | Scientific Literature | ||
11. | ALA4189966 | B | Displacement of [3H]-DTG from human sigma2 receptor expressed in HEK293T cell membranes after 90 mins by scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4262390 | B | Binding affinity to sigma 2 receptor (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA4263501 | B | Displacement of [3H]-ditolylguanidine from human sigma2 receptor expressed in HEKT cells at 10 uM after 90 mins by microbeta scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4303093 | B | Displacement of [3H]-DTG from the Sigma2 receptor | Homo sapiens | 6 | single protein format | SARS-CoV-2 Screening Data 2020-21 | ||
15. | ALA4308647 | B | Displacement of [3H]-Pentazocine from human recombinant sigma2 receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting method | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
16. | ALA4308691 | B | Displacement of [3H]-Pentazocine from human recombinant sigma2 receptor expressed in HEKT cells at 10 uM after 90 mins by microbeta scintillation counting method relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
17. | ALA4315987 | B | Displacement of [3H]-CTG from human recombinant sigma2 receptor expressed in HEKT cells incubated for 90 mins by microbeta scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4369183 | B | Displacement of [3H]-DTG from human sigma 2 receptor | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA4369934 | B | Inhibition of sigma receptor 2 (unknown origin) | Homo sapiens | 15 | single protein format | Scientific Literature | ||
20. | ALA4386110 | B | Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in human RT4 cell membranes at 1 uM after 120 mins in the presence of sigma1 receptor ligand (+)-pentazocine by scintillation counting method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |