# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3562127 | Functional | PubChem BioAssay. Extended Characterization of HPGD Inhibitors: Counterscreen Against LDHA. (Class of assay: confirmatory) | Homo sapiens | ⋯ | ALA1201862 | assay format | PubChem BioAssays | |
2. | ALA3389215 | Binding | Inhibition of LDH (unknown origin) at 10 uM by biochemical assay | Homo sapiens | 2 | ALA3352360 | assay format | Scientific Literature | |
3. | ALA1063155 | Binding | Inhibition of human LDH | Homo sapiens | 3 | ALA1152430 | assay format | Scientific Literature | |
4. | ALA1063159 | Binding | Inhibition of human LDH at 100 uM | Homo sapiens | 8 | ALA1152430 | assay format | Scientific Literature | |
5. | ALA2384172 | Binding | Inhibition of LDH in human HCC1954 cells assessed as lactate accumulation after 6 hrs | Homo sapiens | 1 | ALA2380202 | cell-based format | Scientific Literature | |
6. | ALA2384173 | Binding | Inhibition of LDH in human HCC1954 cells assessed as lactate accumulation up to 50 uM after 6 hrs | Homo sapiens | 3 | ALA2380202 | cell-based format | Scientific Literature | |
7. | ALA4032324 | Binding | Inhibition of LDH in human MIAPaCa2 cells assessed as reduction in lactate production preincubated for 2 hrs measured after 30 mins by high throughput fluorescence assay | Homo sapiens | 49 | ALA4028893 | cell-based format | Scientific Literature | |
8. | ALA4032334 | Binding | Inhibition of LDH in human A673 cells assessed as reduction in lactate production preincubated for 2 hrs measured after 30 mins by high throughput fluorescence assay | Homo sapiens | 49 | ALA4028893 | cell-based format | Scientific Literature | |
9. | ALA4032340 | Binding | Inhibition of LDH in human A673 cells assessed as reduction in glycolytic flux after 40 mins in presence of glucose by glycolysis stress test | Homo sapiens | 5 | ALA4028893 | cell-based format | Scientific Literature | |
10. | ALA4032341 | Binding | Inhibition of LDH in human A673 cells assessed as reduction in maximal ECAR at 2 to 5 uM after 40 mins in presence of glucose by glycolysis stress test | Homo sapiens | 5 | ALA4028893 | cell-based format | Scientific Literature | |
11. | ALA4032364 | Binding | Inhibition of LDH in human A673 cells assessed as reduction in oligomycin-induced switch from oxidative phosphorylation to glycosis | Homo sapiens | 5 | ALA4028893 | cell-based format | Scientific Literature | |
12. | ALA4182155 | ADME | Inhibition of LDH (unknown origin) assessed as reduction in NADH oxidation at 200 uM after 30 mins | Homo sapiens | 1 | ALA4177700 | single protein format | Scientific Literature | |
13. | ALA4222112 | Binding | Inhibition of LDH (unknown origin) at 5 uM using 2-PG relative to control | Homo sapiens | 20 | ALA4219134 | single protein format | Scientific Literature | |
14. | ALA4222114 | Binding | Inhibition of LDH (unknown origin) at 0.625 uM using 2-PG relative to control | Homo sapiens | 1 | ALA4219134 | single protein format | Scientific Literature | |
15. | ALA4255629 | Binding | Inhibition of LDH (unknown origin) assessed as reduction in lactate production by cell-based assay | Homo sapiens | 6 | ALA4251691 | cell-based format | Scientific Literature | |
16. | ALA4396744 | Binding | Substrate activity at lactate dehydrogenase (unknown origin) at 2 mM in presence of NADH | Homo sapiens | 2 | ALA4393736 | single protein format | Scientific Literature | |
17. | ALA4396750 | Binding | Inhibition of lactate dehydrogenase (unknown origin) at 2 mM using pyruvate as substrate in presence of NADH | Homo sapiens | 1 | ALA4393736 | single protein format | Scientific Literature |