# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3991796 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 243 | ALA3991601 | subcellular format | Kuster lab chemical proteomics drug profiling | |
2. | ALA4739643 | B | Stabilization of full length recombinant NAT10 (unknown origin) by DSLS based analysis | Homo sapiens | 3 | ALA4732272 | single protein format | Scientific Literature | |
3. | ALA4739644 | B | Binding affinity to recombinant NAT10 acetyltransferase domain (494 to 753 residues) (unknown origin) by isothermal titration calorimetry | Homo sapiens | 2 | ALA4732272 | single protein format | Scientific Literature | |
4. | ALA4739645 | B | Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C level at 10 to 50 uM after 48 hrs by LC-MS assay | Homo sapiens | 1 | ALA4732272 | cell-based format | Scientific Literature | |
5. | ALA4739646 | B | Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C level at 50 uM after 48 hrs by Northern blot assay | Homo sapiens | 1 | ALA4732272 | cell-based format | Scientific Literature | |
6. | ALA4739647 | B | Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C at helix 34 of 18S rRNA at 50 uM after 4 days by UV-HPLC analysis | Homo sapiens | 1 | ALA4732272 | cell-based format | Scientific Literature | |
7. | ALA4739648 | B | Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C at helix 45 of 18S rRNA at 50 uM after 4 days by UV-HPLC analysis | Homo sapiens | 1 | ALA4732272 | cell-based format | Scientific Literature | |
8. | ALA4739659 | B | Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C level at 10 to 50 uM after 24 to 48 hrs by dot blot assay | Homo sapiens | 1 | ALA4732272 | cell-based format | Scientific Literature | |
9. | ALA4739660 | B | Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C at helix 45 of 18S rRNA at 50 uM after 48 hrs by nucleotide resolution sequencing analysis | Homo sapiens | 1 | ALA4732272 | cell-based format | Scientific Literature |