# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA701956 | B | Compound tested for its ability to inhibit [3H]- KA binding to ionotropic glutamate receptor kainate at the concentration of 100 uM | 4 | ALA1125876 | single protein format | Scientific Literature | ||
2. | ALA701552 | B | Inhibition of [3H]kainate binding at rat forebrain ionotropic glutamate receptor kainate 2 | 29 | ALA1129636 | assay format | Scientific Literature | ||
3. | ALA862730 | B | Displacement of [3H]kainate from rat GLUK6 receptor expressed in HEK293 cells | Rattus norvegicus | 21 | ALA1141230 | cell-based format | Scientific Literature | |
4. | ALA865634 | B | Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells | Rattus norvegicus | 15 | ALA1146072 | cell-based format | Scientific Literature | |
5. | ALA920258 | B | Displacement of [3H]KA from rat recombinant GluR6 expressed in Sf9 cells | Rattus norvegicus | 6 | ALA1139881 | cell-based format | Scientific Literature | |
6. | ALA928082 | B | Activity at rat cloned iGluR6 expressed in human HEK293 cells by calcium imaging assay | Rattus norvegicus | 6 | ALA1142433 | cell-based format | Scientific Literature | |
7. | ALA928083 | B | Activity at rat cloned iGluR6 expressed in human HEK293 cells by calcium imaging assay relative to L-glutamate | Rattus norvegicus | 5 | ALA1142433 | cell-based format | Scientific Literature | |
8. | ALA1013074 | B | Displacement of [3H]SYM2081 from rat cloned iGluR6 | Rattus norvegicus | 3 | ALA1155081 | single protein format | Scientific Literature | |
9. | ALA1013088 | B | Displacement of [3H]SYM2081 from rat recombinant iGluR6 | Rattus norvegicus | 12 | ALA1155082 | single protein format | Scientific Literature | |
10. | ALA1036613 | B | Inhibition of rat recombinant GluR6 expressed in Xenopus oocytes assessed as inhibition of domoate-induced evoked current at 3 uM by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA1140127 | cell-based format | Scientific Literature | |
11. | ALA1036614 | B | Inhibition of rat recombinant GluR6/KA1 expressed in Xenopus oocytes assessed as inhibition of AMPA-induced evoked current at 3 uM by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA1140127 | cell-based format | Scientific Literature | |
12. | ALA1028972 | B | Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cells | Rattus norvegicus | 17 | ALA1140154 | cell-based format | Scientific Literature | |
13. | ALA1059440 | B | Displacement of [3H]KA from rat recombinant GluR6(VCR) RNA-edited isoform expressed in baculovirus infected Sf9 cells | Rattus norvegicus | 3 | ALA1151943 | cell-based format | Scientific Literature | |
14. | ALA1062121 | F | Agonist activity at rat recombinant GluR6(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assay | Rattus norvegicus | 5 | ALA1151943 | cell-based format | Scientific Literature | |
15. | ALA1062122 | F | Agonist activity at rat recombinant GluR6(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assay relative to glutamic acid | Rattus norvegicus | 1 | ALA1151943 | cell-based format | Scientific Literature | |
16. | ALA1047802 | F | Antagonist activity at rat recombinant GluR6 expressed in Xenopus laevis oocytes assessed as inhibition of concanavalin A/glutamate-induced current at 3 uM by two electrode voltage clamp method relative to control | Rattus norvegicus | 23 | ALA1152519 | cell-based format | Scientific Literature | |
17. | ALA1040715 | F | Antagonist activity at rat recombinant GluR6 expressed in Xenopus laevis oocytes assessed as inhibition of concanavalin A/glutamate-induced current at 3 uM by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA1152519 | cell-based format | Scientific Literature | |
18. | ALA1064563 | B | Displacement of [3H]SYM2081 from rat recombinant iGluR6 expressed in baculovirus-infected insect Sf9 cells | Rattus norvegicus | 24 | ALA1152523 | cell-based format | Scientific Literature | |
19. | ALA1104011 | B | Displacement of [3H]SYM2081 from rat iGluR6 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | Rattus norvegicus | 4 | ALA1157748 | cell-based format | Scientific Literature | |
20. | ALA1219915 | F | Antagonist activity at rat recombinant GLuR6 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 17 | ALA1212913 | cell-based format | Scientific Literature |