# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA701956 | B | Compound tested for its ability to inhibit [3H]- KA binding to ionotropic glutamate receptor kainate at the concentration of 100 uM | 4 | single protein format | Scientific Literature | |||
2. | ALA701552 | B | Inhibition of [3H]kainate binding at rat forebrain ionotropic glutamate receptor kainate 2 | 29 | assay format | Scientific Literature | |||
3. | ALA862730 | B | Displacement of [3H]kainate from rat GLUK6 receptor expressed in HEK293 cells | Rattus norvegicus | 21 | cell-based format | Scientific Literature | ||
4. | ALA865634 | B | Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
5. | ALA920258 | B | Displacement of [3H]KA from rat recombinant GluR6 expressed in Sf9 cells | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
6. | ALA1817065 | B | Displacement of [3H]SYM2081 from rat GluK2 expressed in Sf9 cells | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
7. | ALA928082 | B | Activity at rat cloned iGluR6 expressed in human HEK293 cells by calcium imaging assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
8. | ALA928083 | B | Activity at rat cloned iGluR6 expressed in human HEK293 cells by calcium imaging assay relative to L-glutamate | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
9. | ALA1013074 | B | Displacement of [3H]SYM2081 from rat cloned iGluR6 | Rattus norvegicus | 3 | single protein format | Scientific Literature | ||
10. | ALA1013088 | B | Displacement of [3H]SYM2081 from rat recombinant iGluR6 | Rattus norvegicus | 12 | single protein format | Scientific Literature | ||
11. | ALA1036613 | B | Inhibition of rat recombinant GluR6 expressed in Xenopus oocytes assessed as inhibition of domoate-induced evoked current at 3 uM by two electrode voltage clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
12. | ALA1036614 | B | Inhibition of rat recombinant GluR6/KA1 expressed in Xenopus oocytes assessed as inhibition of AMPA-induced evoked current at 3 uM by two electrode voltage clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
13. | ALA1028972 | B | Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cells | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
14. | ALA1059440 | B | Displacement of [3H]KA from rat recombinant GluR6(VCR) RNA-edited isoform expressed in baculovirus infected Sf9 cells | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
15. | ALA1062121 | F | Agonist activity at rat recombinant GluR6(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assay | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
16. | ALA1062122 | F | Agonist activity at rat recombinant GluR6(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assay relative to glutamic acid | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
17. | ALA1047802 | F | Antagonist activity at rat recombinant GluR6 expressed in Xenopus laevis oocytes assessed as inhibition of concanavalin A/glutamate-induced current at 3 uM by two electrode voltage clamp method relative to control | Rattus norvegicus | 23 | cell-based format | Scientific Literature | ||
18. | ALA1040715 | F | Antagonist activity at rat recombinant GluR6 expressed in Xenopus laevis oocytes assessed as inhibition of concanavalin A/glutamate-induced current at 3 uM by two electrode voltage clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
19. | ALA1064563 | B | Displacement of [3H]SYM2081 from rat recombinant iGluR6 expressed in baculovirus-infected insect Sf9 cells | Rattus norvegicus | 24 | cell-based format | Scientific Literature | ||
20. | ALA1104011 | B | Displacement of [3H]SYM2081 from rat iGluR6 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | Rattus norvegicus | 4 | cell-based format | Scientific Literature |