# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1738436 | Functional | PUBCHEM_BIOASSAY: Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction in luminescent format. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485346, AID488776] | Homo sapiens | 20 | ALA1201862 | assay format | PubChem BioAssays | |
2. | ALA4019945 | Binding | Inhibition of MDM2/MDMX in human SH-SY5Y cells assessed as accumulation of p53 at 1 uM after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
3. | ALA4019961 | Binding | Inhibition of MDM2/MDMX in human SH-SY5Y cells assessed as increase in MDM2 mRNA levels at 1 uM after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
4. | ALA4019962 | Binding | Inhibition of MDM2/MDMX in human SH-SY5Y cells assessed as increase in PUMA mRNA levels at 1 uM after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature | |
5. | ALA4019963 | Binding | Inhibition of MDM2/MDMX in human SH-SY5Y cells assessed as increase in p21 mRNA levels at 1 uM after 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4017523 | cell-based format | Scientific Literature |