# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3991966 | B | Inhibition of c-Myc/Max interaction in human HL60 cells assessed as cell growth inhibition after 5 days by trypan blue exclusion assay | Homo sapiens | 12 | ALA3991942 | cell-based format | Patent Bioactivity Data | |
2. | ALA3991967 | B | Inhibition of c-Myc/Max interaction in human HL60 nuclear extracts at 100 to 200 uM after 30 mins by co-immunoprecipitation assay | Homo sapiens | 12 | ALA3991942 | protein format | Patent Bioactivity Data | |
3. | ALA3991970 | B | Inhibition of recombinant human His6 tagged c-Myc bHLH-LZ domain (353 to 439 residues) with GGCD extension at C-terminus/recombinant human full length His6 tagged Max (151 residues) expressed in Escherichia coli assessed as reduction of heterodimer binding to HEX labeled E-box-containing DNA after 90 mins by electrophoretic mobility shift assay | Homo sapiens | 12 | ALA3991942 | assay format | Patent Bioactivity Data | |
4. | ALA3992300 | B | Inhibition of recombinant c-Myc/Max (unknown origin) expressed in human HL60 cells assessed as disruption of c-Myc/Max association after 6 hrs by co-immunoprecipitation assay | Homo sapiens | 4 | ALA3991946 | cell-based format | Patent Bioactivity Data | |
5. | ALA3992301 | B | Inhibition of recombinant c-Myc/Max (unknown origin) expressed in human HL60 cells assessed as disruption of c-Myc/Max association after 16 hrs by co-immunoprecipitation assay | Homo sapiens | 4 | ALA3991946 | cell-based format | Patent Bioactivity Data | |
6. | ALA4678160 | B | Inhibition of Nanoluc-tagged c-Myc/Halo-tagged MAX (unknown origin) interaction expressed in HEK293T cells assessed as degradation measured after 4 to 6 hrs by NanoBRET assay | Homo sapiens | 1 | ALA4673326 | cell-based format | Scientific Literature | |
7. | ALA4836926 | B | Disruption of interaction between human recombinant GST-tagged MAX/VF-tagged MYC expressed in HEK293T cells at 50 uM incubated for 30 mins by GST pull-down assay | Homo sapiens | 1 | ALA4834479 | cell-based format | Scientific Literature | |
8. | ALA5236767 | B | Inhibition of Myc/Max (unknown origin) | Homo sapiens | 4 | ALA5236544 | protein format | Scientific Literature |