| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4031004 | B | Inhibition of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as decrease in endothelin-1 induced mRNA level of ANP at 10 uM preincubated for 1 hr followed by endothelin-1 addition measured after 23 hrs by real-time PCR analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 2. | ALA4031005 | B | Inhibition of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as decrease in basal mRNA level of ANP at 10 uM after 24 hrs by real-time PCR analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 3. | ALA4031006 | B | Inhibition of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as decrease in endothelin-1 induced mRNA level of BNP at 10 uM preincubated for 1 hr followed by endothelin-1 addition measured after 23 hrs by real-time PCR analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 4. | ALA4031007 | B | Inhibition of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as decrease in basal mRNA level of BNP at 10 uM after 24 hrs by real-time PCR analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 5. | ALA4031008 | B | Inhibition of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocyte hypertrophy model assessed as decrease in mechanical stretching-induced cell surface area at 10 uM after 48 hrs by alpha-actinin/phalloidin/DAPI staining-based fluorescence microscopic method | Rattus norvegicus | 1 | protein complex format | Scientific Literature | ||
| 6. | ALA4031038 | B | Inhibition of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as decrease in endothelin-1 induced mRNA level of ANP at 20 uM preincubated for 1 hr followed by endothelin-1 addition measured after 23 hrs by real-time PCR analysis | Rattus norvegicus | 4 | assay format | Scientific Literature | ||
| 7. | ALA4031039 | B | Inhibition of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as decrease in endothelin-1 induced mRNA level of BNP at 20 uM preincubated for 1 hr followed by endothelin-1 addition measured after 23 hrs by real-time PCR analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 8. | ALA4031040 | B | Activation of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as increase in basal mRNA level of ANP at 20 uM after 24 hrs by real-time PCR analysis relative to control | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 9. | ALA4031041 | B | Activation of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as increase in basal mRNA level of BNP at 20 uM after 24 hrs by real-time PCR analysis relative to control | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 10. | ALA4031042 | B | Activation of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as increase in endothelin-1 induced mRNA level of BNP at 20 uM preincubated for 1 hr followed by endothelin-1 addition measured after 23 hrs by real-time PCR analysis relative to control | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 11. | ALA4031043 | B | Activation of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as increase in basal mRNA level of ANP at 100 uM after 24 hrs by real-time PCR analysis relative to control | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 12. | ALA4031044 | B | Activation of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as increase in basal mRNA level of BNP at 100 uM after 24 hrs by real-time PCR analysis relative to control | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 13. | ALA4322418 | B | Modulation of GATA4/NKX2-5 protein-protein interaction in neonatal Wistar rat cardiomyocytes harboring -534/+4 bp rat BNP proximal promoter assessed as increase in BNP-promoter driven activity at 10 to 30 preincubated for 1 hr followed by hypertrophic agonist endothelin-1 and measured after 24 hrs by luminescence method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4322419 | B | Modulation of GATA4/NKX2-5 protein-protein interaction in neonatal Wistar rat cardiomyocytes harboring -534/+4 bp rat BNP proximal promoter assessed as reduction in BNP-promoter driven activity at 10 to 30 preincubated for 1 hr followed by hypertrophic agonist endothelin-1 and measured after 24 hrs by luminescence method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4322423 | B | Modulation of GATA4/NKX2-5 protein-protein interaction in neonatal Wistar rat cardiomyocytes harboring -534/+4 bp rat BNP proximal promoter assessed as reduction in hypertrophic response at 30 preincubated for 1 hr followed by hypertrophic agonist endothelin-1 and measured after 24 hrs by luminescence method | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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