| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4023028 | B | Inhibition of full length recombinant human ATR /ATRIP at 1 uM relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 2. | ALA4256221 | B | Inhibition of recombinant human full length ATR/ATRIP expressed in mammalian expression system using c-Myc-tagged p53 as substrate incubated for 15 mins followed by substrate addition measured after 25 to 35 mins by TR-FRET assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 3. | ALA4766982 | B | Inhibition of recombinant full-length human ATR/ATRIP assessed as residual activity at 10 uM using GST-cMyc-p53 as substrate measured after 40 mins by fluorescence assay relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 4. | ALA4775106 | B | Displacement of 5-TAMRA-labelled Tracer A from human GST-fused/FLAG-tagged full length ATR/human N-terminal FLAG-tagged full length ATRIP expressed in HEK293-6E cells incubated for 15 mins by TR-FRET based competition binding assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4839364 | B | Displacement of 5-TAMRA-labelled Tracer A from human GST-fused/FLAG-tagged full length ATR/human N-terminal FLAG-tagged full length ATRIP expressed in HEK293-6E cells preincubated for 15 mins followed by tracer A addition and measured after 30 mins by TR-FRET based competition binding assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 6. | ALA4881291 | B | ATR/ATRIP(h) Eurofins Kinase panel | Homo sapiens | 1 | protein complex format | Donated Chemical Probes - SGC Frankfurt | ||
| 7. | ALA4881473 | B | ATR/ATRIP(h) Eurofins Kinase panel | Homo sapiens | 1 | protein complex format | Donated Chemical Probes - SGC Frankfurt | ||
| 8. | ALA4884529 | B | ATR/ATRIP(h) Eurofins kinase panel | Homo sapiens | 1 | protein complex format | Donated Chemical Probes - SGC Frankfurt | ||
| 9. | ALA4887779 | B | ATR/ATRIP(h) Millipore kinase panel | Homo sapiens | 1 | protein complex format | Donated Chemical Probes - SGC Frankfurt | ||
| 10. | ALA5117585 | B | Inhibition of human ATR/ATRIP assessed as residual activity at 10 uM relative to control | Homo sapiens | 3 | protein complex format | Scientific Literature | ||
| 11. | ALA5127715 | B | Inhibition of full-length human recombinant FLAG-tagged ATR/c-Myc-tagged ATRIP using p53 as substrate incubated for 30 mins in presence of ATP by fluorescence based assay | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 12. | ALA5127718 | B | Inhibition of human FLAG-tagged ATR/c-Myc-tagged ATRIP expressed in mammalian expression system using p53 as substrate incubated for 2 hrs by fluorescence based assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 13. | ALA5127720 | B | Inhibition of full-length human recombinant FLAG-tagged ATR/c-Myc-tagged ATRIP using p53 as substrate incubated for 30 mins in presence of ATP by HTRF assay | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 14. | ALA5127721 | B | Inhibition of full-length recombinant human ATR/ATRIP using p53 as substrate incubated for 30 mins in presence of ATP by HTRF assay | Homo sapiens | 2 | protein complex format | Scientific Literature |
The page will load shortly, Thanks for your patience!