# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1816622 | B | Modulation of GABA Aalpha1beta3 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding potential -70 mV by two-microelectrode voltage clamp technique | 1 | cell-based format | Scientific Literature | |||
2. | ALA1816891 | B | Modulation of GABA Aalpha1beta3 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding potential -70 mV by two-microelectrode voltage clamp technique relative to GABA | 1 | cell-based format | Scientific Literature | |||
3. | ALA2168417 | B | Binding affinity to human FLAG-tagged alpha1beta3 GABA A receptor expressed in HEK293S cells assessed as receptor photolabeling using [3H]-labeled compound by Coomassie blue staining based SDS-PAGE and liquid scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA3073012 | B | Displacement of [3H]EBOB from recombinant Homo sapiens (human) GABA alpha1beta3 receptor | Homo sapiens | 3 | assay format | Scientific Literature | ||
5. | ALA4219595 | B | Positive allosteric modulation of recombinant human GABAA receptor alpha1beta3 expressed in Xenopus oocytes assessed as potentiation of GABA induced chloride current response relative to GABA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4269833 | B | Positive allosteric modulation of GABAA receptor alpha1beta3 (unknown origin) expressed in Xenopus laevis oocytes assessed as GABA-stimulated current amplitude at 1 to 10 uM up to 120 secs by electrophysiological method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA4686850 | B | Positive allosteric modulation of GABAA alpha1beta3 in HEK cell plasma membrane assessed as increase in [3H]muscimol binding measured after 10 mins by liquid scintillation counting method | Homo sapiens | 1 | cell membrane format | Scientific Literature |