| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4017152 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 1 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay relative to cisplatin alone | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4017153 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 0.5 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay relative to cisplatin alone | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4017215 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 100 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4017216 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 200 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4017217 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 300 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4017218 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 400 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4017219 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 500 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4017220 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 600 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4017221 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 700 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4017222 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 800 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4017223 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 900 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4017224 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 1000 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4017225 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 1500 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4017226 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 2000 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4017227 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 3.16 uM cisplatin-induced cytotoxicity by measuring combination index at 100 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4017228 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 3.16 uM cisplatin-induced cytotoxicity by measuring combination index at 200 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4017229 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 3.16 uM cisplatin-induced cytotoxicity by measuring combination index at 300 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4017230 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 3.16 uM cisplatin-induced cytotoxicity by measuring combination index at 400 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4017231 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 3.16 uM cisplatin-induced cytotoxicity by measuring combination index at 500 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA4017232 | B | Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 3.16 uM cisplatin-induced cytotoxicity by measuring combination index at 600 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
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