#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4149701	B	Inhibition of Mycobacterium tuberculosis H37Ra PTPB expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition measured for 5 mins by spectrophotometric analysis	Mycobacterium tuberculosis H37Ra	2		assay format	Scientific Literature
2.	ALA4149702	B	Inhibition of Mycobacterium tuberculosis H37Ra PTPB expressed in Escherichia coli BL21 (DE3) at 50 uM using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition measured for 5 mins by spectrophotometric analysis	Mycobacterium tuberculosis H37Ra	12		assay format	Scientific Literature
3.	ALA4192451	B	Inhibition of Mycobacterium tuberculosis PTPB	Mycobacterium tuberculosis	2		single protein format	Scientific Literature
4.	ALA4200234	B	Inhibition of Mycobacterium PTPB at 50 uM using p-nitrophenyl phosphate as substrate incubated for 10 mins followed by substrate addition and measured for 5 mins by spectrophotometric method	Mycobacterium	22		single protein format	Scientific Literature
5.	ALA4201103	B	Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins	Mycobacterium tuberculosis H37Rv	13		assay format	Scientific Literature
6.	ALA4201141	B	Inhibition of Mycobacterium tuberculosis H37Rv ATCC 35837 ptpB infected in human THP1 cells assessed as reduction in intracellular bacterial burden at 20 to 100 uM after 72 hrs post infection relative to DMSO-treated control	Mycobacterium tuberculosis H37Rv	1		cell-based format	Scientific Literature
7.	ALA4201142	B	Inhibition of multi-drug resistant Mycobacterium tuberculosis Beijing-W_565 ptpB infected in human THP1 cells assessed as reduction in intracellular bacterial burden at 20 to 100 uM after 72 hrs post infection relative to DMSO-treated control	Mycobacterium tuberculosis	1		cell-based format	Scientific Literature
8.	ALA4201158	B	Inhibition of Mycobacterium tuberculosis H37Rv ATCC 35837 ptpB infected in human THP1 cells assessed as reduction in intracellular bacterial burden at 10 to 80 uM after 72 hrs post infection relative to DMSO-treated control	Mycobacterium tuberculosis H37Rv	1		cell-based format	Scientific Literature
9.	ALA4201159	B	Inhibition of multi-drug resistant Mycobacterium tuberculosis Beijing-W_565 ptpB infected in human THP1 cells assessed as reduction in intracellular bacterial burden at 20 to 80 uM after 72 hrs post infection relative to DMSO-treated control	Mycobacterium tuberculosis	1		cell-based format	Scientific Literature
10.	ALA4201160	B	Inhibition of RFP expressing Mycobacterium tuberculosis H37Rv ATCC 35837 ptpB infected in mouse RAW264.7 cells assessed as prolongation association of PI3P to FYVE2X-FGFP on bacterial phagosome at 80 uM by live-cell imaging method	Mycobacterium tuberculosis H37Rv	1		cell-based format	Scientific Literature
11.	ALA4253916	B	Inhibition of Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition measured every minute for 10 mins by UV-VIS spectrophotometric analysis	Mycobacterium tuberculosis	9		single protein format	Scientific Literature
12.	ALA4253924	B	Competitive inhibition of Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate up to 0.3 uM preincubated for 10 mins followed by substrate addition measured every minute for 10 mins by Michaelis-Menten plot analysis	Mycobacterium tuberculosis	1		single protein format	Scientific Literature
13.	ALA4253925	B	Non-competitive inhibition of Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate up to 0.3 uM preincubated for 10 mins followed by substrate addition measured every minute for 10 mins by Michaelis-Menten plot analysis	Mycobacterium tuberculosis	1		single protein format	Scientific Literature
14.	ALA4253926	B	Inhibition of Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition measured every minute for 10 mins by Michaelis-Menten plot analysis	Mycobacterium tuberculosis	2		single protein format	Scientific Literature
15.	ALA4253927	B	Reversible inhibition of Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate assessed as enzyme recovery at 10 times IC50 preincubated for 10 mins followed by 100-fold dilution	Mycobacterium tuberculosis	2		single protein format	Scientific Literature
16.	ALA4253930	B	Binding affinity to Mycobacterium tuberculosis PtpB assessed as Stern-Volmer quenching constant by UV-VIS spectrophotometric analysis	Mycobacterium tuberculosis	2		single protein format	Scientific Literature
17.	ALA4253931	B	Binding affinity to Mycobacterium tuberculosis PtpB by UV-VIS spectrophotometric analysis	Mycobacterium tuberculosis	2		single protein format	Scientific Literature
18.	ALA4253936	B	Time independent inhibition of Mycobacterium tuberculosis PtpB at 0.2 uM pre-incubated for 0 to 10 mins before p-nitrophenyl phosphate substrate addition	Mycobacterium tuberculosis	2		single protein format	Scientific Literature
19.	ALA4253937	B	Binding affinity to Mycobacterium tuberculosis PtpB assessed as fluorescence quenching at 0.1 to 4.7 uM by spectropolarimetry	Mycobacterium tuberculosis	1		single protein format	Scientific Literature
20.	ALA4253938	B	Binding affinity to Mycobacterium tuberculosis PtpB assessed as fluorescence quenching at 0.1 to 3.8 uM by spectropolarimetry	Mycobacterium tuberculosis	1		single protein format	Scientific Literature