# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4201111 | B | Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden at 10 to 120 uM after 72 hrs post infection relative to DMSO-treated control | Mycobacterium tuberculosis variant bovis BCG | 5 | ALA4196176 | cell-based format | Scientific Literature | |
2. | ALA4201112 | B | Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden at 10 to 120 uM after 24 hrs post infection | Mycobacterium tuberculosis variant bovis BCG | 5 | ALA4196176 | cell-based format | Scientific Literature | |
3. | ALA4201113 | B | Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden at 80 uM after 72 hrs post infection | Mycobacterium tuberculosis variant bovis BCG | 4 | ALA4196176 | cell-based format | Scientific Literature | |
4. | ALA4201139 | B | Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden up to 500 uM after 72 hrs post infection relative to treated-DMSO control | Mycobacterium tuberculosis variant bovis BCG | 1 | ALA4196176 | cell-based format | Scientific Literature | |
5. | ALA4201145 | B | Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden at 5 uM after 72 hrs post infection in presence of isoniazid | Mycobacterium tuberculosis variant bovis BCG | 1 | ALA4196176 | cell-based format | Scientific Literature | |
6. | ALA4201146 | B | Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden at 5 uM after 72 hrs post infection in presence of rifampicin | Mycobacterium tuberculosis variant bovis BCG | 1 | ALA4196176 | cell-based format | Scientific Literature |