# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA746417 | B | Inhibition of [3H]pirenzepine binding to mouse muscarinic acetylcholine receptor M1 from cerebral cortex | Mus musculus | 15 | ALA1125532 | tissue-based format | Scientific Literature | |
2. | ALA746423 | B | Tested against Muscarinic acetylcholine receptor M1 expressed in A9 L cell line | Mus musculus | 20 | ALA1129993 | cell-based format | Scientific Literature | |
3. | ALA746424 | B | Binding affinity against mouse Muscarinic acetylcholine receptor M1 using cerebral cortex and [3H]pirenzepine | 2 | ALA1125532 | tissue-based format | Scientific Literature | ||
4. | ALA746425 | B | Binding affinity against mouse muscarinic acetylcholine receptor M1 using cerebral cortex and [3H]pirenzepine | 2 | ALA1125532 | tissue-based format | Scientific Literature | ||
5. | ALA745515 | B | Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to Muscarinic acetylcholine receptor M1 of mouse cerebral cortex | 9 | ALA1125408 | tissue-based format | Scientific Literature | ||
6. | ALA748961 | B | Compound was evaluated for the competitive inhibition of [3H]pirenzepine binding to muscarinic acetylcholine receptor M1 of mouse cerebral cortex | 6 | ALA1125408 | tissue-based format | Scientific Literature | ||
7. | ALA748962 | B | Percent inhibition (high) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the absence of 300 uM GTP-gamma-S | 1 | ALA1129993 | cell-based format | Scientific Literature | ||
8. | ALA748963 | B | Percent inhibition (high) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the absence of 300 uM GTP-gamma-S | Mus musculus | 6 | ALA1129993 | cell-based format | Scientific Literature | |
9. | ALA748964 | B | Percent inhibition (low) of [3H]-(R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the absence of 300 uM GTP-gamma-S | Mus musculus | 9 | ALA1129993 | cell-based format | Scientific Literature | |
10. | ALA748965 | B | Percent inhibition of [3H]-(R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the presence of 300 uM GTP-gamma-S | Mus musculus | 5 | ALA1129993 | cell-based format | Scientific Literature | |
11. | ALA748966 | B | Compound was evaluated for the affinity at the cloned radio labelled Muscarinic acetylcholine receptor M1 | 4 | ALA1131247 | single protein format | Scientific Literature | ||
12. | ALA748967 | B | Binding affinity (high) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the absence of 300 uM GTP-gamma-S | Mus musculus | 7 | ALA1129993 | cell-based format | Scientific Literature | |
13. | ALA748968 | B | Binding affinity (low) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the absence of 300 uM GTP-gamma-S | Mus musculus | 9 | ALA1129993 | cell-based format | Scientific Literature | |
14. | ALA748051 | B | Binding affinity of [3H]-(R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the presence of 300 uM GTP-gamma-S | Mus musculus | 4 | ALA1129993 | cell-based format | Scientific Literature | |
15. | ALA748052 | F | Maximum stimulation at Muscarinic acetylcholine receptor M1 expressed in A9 L cells | 21 | ALA1129993 | cell-based format | Scientific Literature | ||
16. | ALA748056 | B | Binding affinity of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the presence of 300 uM GTP-gamma-S | Rattus norvegicus | 1 | ALA1129993 | cell-based format | Scientific Literature | |
17. | ALA1803793 | F | Agonist activity at mouse muscarinic M1 receptor expressed in CHOK1 cells assessed as potentiation of acetylcholine-induced calcium mobilization preincubated for 4 mins measured after 1 hr by FLIPR assay | Mus musculus | 1 | ALA1799933 | cell-based format | Scientific Literature | |
18. | ALA4199653 | F | Positive allosteric modulation of mouse muscarinic acetylcholine receptor M1 expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreated for 4 mins followed by acetylcholine addition and measured after 4 mins by Fluo-4-AM dye based FLIPR assay | Mus musculus | 1 | ALA4196115 | cell-based format | Scientific Literature |