| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4123975 | B | Inhibition of Dengue virus 2 NS5 full length RdRp activity using RNA as template/primer assessed as inhibition of [alpha3P]GTP incorporation by SDS-PAGE analysis | dengue virus type 2 | 1 | ALA4118212 | single protein format | Scientific Literature | |
| 2. | ALA4123978 | B | Inhibition of Dengue virus 4 NS5 full length RdRp activity using RNA as template assessed as inhibition of NTPs incorporation after 90 mins by FAPA assay | dengue virus type 4 | 1 | ALA4118212 | single protein format | Scientific Literature | |
| 3. | ALA4123982 | B | Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 mins | Dengue virus | 9 | ALA4118212 | single protein format | Scientific Literature | |
| 4. | ALA4252297 | B | Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based fluorescence assay | dengue virus type 3 | 23 | ALA4251565 | single protein format | Scientific Literature | |
| 5. | ALA4252298 | B | Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of ss-RNA PolyC as template assessed as enzyme Vmax after 1 hr in presence of GTP substrate by Lineweaver-Burk double reciprocal plot analysis | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 6. | ALA4252299 | B | Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of ss-RNA PolyC as template assessed as Km for substrate after 1 hr in presence of GTP substrate after 1 hr by Lineweaver-Burk double reciprocal plot analysis | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 7. | ALA4252300 | B | Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of ss-RNA PolyC as template assessed as free enzyme after 1 hr in presence of GTP substrate by Lineweaver-Burk double reciprocal plot analysis | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 8. | ALA4252301 | B | Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of ss-RNA PolyC as template assessed as enzyme-substrate complex after 1 hr in presence of GTP substrate by Lineweaver-Burk double reciprocal plot analysis | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 9. | ALA4252302 | B | Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of GTP as substrate assessed as enzyme Vmax after 1 hr in presence of ss-RNA PolyC template by Lineweaver-Burk double reciprocal plot analysis | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 10. | ALA4252303 | B | Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of GTP as substrate assessed as Km for substrate after 1 hr in presence of ss-RNA PolyC template by Lineweaver-Burk double reciprocal plot analysis | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 11. | ALA4252304 | B | Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of GTP as substrate assessed as free enzyme after 1 hr in presence of ss-RNA PolyC template by Lineweaver-Burk double reciprocal plot analysis | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 12. | ALA4252305 | B | Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of GTP as substrate assessed as enzyme-substrate complex after 1 hr in presence of ss-RNA PolyC template by Lineweaver-Burk double reciprocal plot analysis | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 13. | ALA4252306 | B | Binding affinity to DENV3 NT-647-NHS labeled NS5 RdRp after 1 hr by microscale thermophoresis method | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 14. | ALA4252307 | B | Binding affinity to DENV3 NT-647-NHS labeled NS5 RdRp after 1 hr in presence of ss-RNA PolyC as template and GTP as substrate by microscale thermophoresis method | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 15. | ALA4252313 | B | Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr in presence of tritonX100 by PicoGreen-based fluorescence assay | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 16. | ALA4252315 | B | Inhibition of DENV3 full length NS5 RdRp assessed as decrease in dsRNA levels preincubated for 20 mins followed by ss-RNA and ATTO-CTP, ATP, GTP and UTP addition measured after 120 mins by FAPA assay | dengue virus type 3 | 1 | ALA4251565 | single protein format | Scientific Literature | |
| 17. | ALA4327417 | B | Inhibition of DENV3 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation counting method | dengue virus type 3 | 22 | ALA4325865 | single protein format | Scientific Literature | |
| 18. | ALA4398320 | B | Inhibition of recombinant N-terminal His6-tagged DENV2 NGC NS5 RNA dependent RNA polymerase | dengue virus type 2 | 1 | ALA4396891 | single protein format | Scientific Literature | |
| 19. | ALA4398325 | B | Inhibition of His-tagged DENV2 NS5 RNA dependent RNA polymerase expressed in baculovirus infected sf9 cells | dengue virus type 2 | 1 | ALA4396891 | cell-based format | Scientific Literature | |
| 20. | ALA4398326 | B | Inhibition of His-tagged DENV2 NS5 RNA dependent RNA polymerase | dengue virus type 2 | 1 | ALA4396891 | single protein format | Scientific Literature |
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