# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4268729 | B | Inhibition of Escherichia coli NDM4 assessed as potentiation of meropenem-induced antibacterial activity by measuring zone of inhibition at 10 uL after 16 to 18 hrs by disc diffusion method (Rvb = 9.6 +/- 0.5 millimeter) | Escherichia coli | 9 | single protein format | Scientific Literature | ||
2. | ALA4387835 | B | Inhibition of NDM4 in Escherichia coli isolate 3 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC after 24 hrs by broth microdilution assay (Rvb = 1280 ug/ml) | Escherichia coli | 3 | single protein format | Scientific Literature | ||
3. | ALA4387838 | B | Inhibition of NDM4 in Escherichia coli ATCC 25922 assessed as potentiation of meropenem-induced antibacterial activity by measuring diameter of inhibition zone measured after 18 hrs by agar disk diffusion method | Escherichia coli ATCC 25922 | 2 | single protein format | Scientific Literature | ||
4. | ALA4387840 | B | Inhibition of NDM4 in Escherichia coli ATCC 25922 assessed as potentiation of meropenem-induced antibacterial activity by measuring zone of inhibition by agar disk diffusion method (Rvb = 9.8 millimeter) | Escherichia coli ATCC 25922 | 3 | single protein format | Scientific Literature | ||
5. | ALA4387853 | B | Inhibition of NDM4 in Escherichia coli isolate 3 assessed as potentiation of meropenem-induced bactericidal activity by measuring bacterial killing in early exponential phase at 64 ug/ml incubated for 24 hrs followed by replating on agar plates for 16 to 18 hrs and measured up to 24 hrs by time kill assay | Escherichia coli | 2 | single protein format | Scientific Literature | ||
6. | ALA4387854 | B | Inhibition of NDM4 in Escherichia coli isolate 3 assessed as potentiation of meropenem-induced bactericidal activity by measuring bacterial killing in late exponential phase at 64 ug/ml incubated for 24 hrs followed by replating on agar plates for 16 to 18 hrs and measured up to 24 hrs by time kill assay | Escherichia coli | 2 | single protein format | Scientific Literature | ||
7. | ALA4387855 | B | Inhibition of NDM4 in Escherichia coli isolate 3 assessed as potentiation of meropenem-induced bactericidal activity at 4 times MIC incubated for 24 hrs followed by replating on agar plates for 16 to 18 hrs and measured up to 24 hrs by time kill assay | Escherichia coli | 3 | single protein format | Scientific Literature | ||
8. | ALA4387856 | B | Inhibition of NDM4 in Escherichia coli isolate 3 assessed as potentiation of meropenem-induced bactericidal activity by measuring log reduction in bacterial colonies at 64 ug/ml incubated for 24 hrs followed by replating on agar plates for 16 to 18 hrs and measured up to 24 hrs by time kill assay | Escherichia coli | 1 | single protein format | Scientific Literature | ||
9. | ALA4387867 | B | Inhibition of Escherichia coli NDM4 assessed as potentiation of meropenem-induced antibacterial activity by measuring reduction in bacterial growth at 64 ug/mL after 24 hrs by broth microdilution method relative to control | Escherichia coli | 3 | single protein format | Scientific Literature | ||
10. | ALA4387868 | B | Inhibition of Escherichia coli NDM4 assessed as potentiation of meropenem-induced antibacterial activity by measuring bacterial growth rate at 64 ug/mL after 24 hrs in presence of ZnCl2 by broth microdilution method relative to control | Escherichia coli | 3 | single protein format | Scientific Literature | ||
11. | ALA4387869 | B | Inhibition of Escherichia coli isolate 3 NDM4 assessed as potentiation of meropenem-induced antibacterial activity by measuring reduction in meropenem MIC after 24 hrs by broth microdilution method relative to meropenem alone | Escherichia coli | 2 | single protein format | Scientific Literature | ||
12. | ALA4387870 | B | Inhibition of NDM4 in Escherichia coli isolate 3 assessed as potentiation of meropenem-induced bactericidal activity by measuring bacterial killing at 64 ug/ml incubated for 24 hrs followed by replating on agar plates for 16 to 18 hrs and measured up to 24 hrs by time kill assay relative to control | Escherichia coli | 1 | single protein format | Scientific Literature |