| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4136611 | B | Inhibition of cystathionine gamma-lyase (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 2. | ALA4136612 | B | Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM at 40 uM using L-cystathionine incubated for 7 mins by fluorescence-based primary assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA4136613 | B | Reversible inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine at 50 uM incubated for 2 hrs followed by dialysis for 18 to 48 hrs by fluorescence-based primary assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4136614 | B | Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in H2S production at 40 uM using AzMC probe by fluorescence based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4136616 | B | Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for 15 min followed by L-cystathionine and CPM addition and measured after 7 mins by fluorescence-based primary assay | Homo sapiens | 41 | single protein format | Scientific Literature | ||
| 6. | ALA4138487 | B | Inhibition of N-terminal His-tagged CSE extracted from human HepG2 cells expressed in Escherichia coli BL21 (DE3) using methylcysteine as substrate measured for 10 mins by CPM probe-based fluorescence assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA4138489 | B | Inhibition of N-terminal His-tagged CSE extracted from human HepG2 cells expressed in Escherichia coli BL21 (DE3) using cysteine as substrate assessed as decrease in H2S production preincubated for 3 mins in presence of lead nitrate followed by cysteine addition | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 8. | ALA4675259 | B | Inhibition of human CSE expressed in HEK293T cells assessed as reduction in H2S contents at 20 to 50 uM by lead acetate assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4675261 | B | Inhibition of human CSE R119K mutant expressed in HEK293T cells assessed as reduction in H2S contents at 200 to 500 uM by lead acetate assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4675262 | B | Inhibition of human CSE Y114F mutant expressed in HEK293T cells assessed as reduction in H2S contents at 200 to 500 uM by lead acetate assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4675263 | B | Inhibition of human CSE R119A mutant expressed in HEK293T cells assessed as reduction in H2S contents at 200 to 500 uM by lead acetate assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4675265 | B | Inhibition of human CSE R119K mutant expressed in HEK293T cells assessed as reduction in H2S contents | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4675266 | B | Inhibition of human CSE Y114F mutant expressed in HEK293T cells assessed as reduction in H2S contents | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4675267 | B | Inhibition of human CSE R119A mutant expressed in HEK293T cells assessed as reduction in H2S contents | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4675271 | B | Inhibition of wild type human CSE expressed in HEK293T cells assessed as reduction in H2S contents | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4675275 | B | Inhibition of human CSE expressed in mouse RAW264.7 cells assessed as reduction in amount of released H2S level at >=200 uM by lead acetate method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4675277 | B | Inhibition of human CSE expressed in mouse RAW264.7 cells assessed as reduction in amount of released H2S level at 20 to 50 uM by lead acetate method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4675288 | B | Competitive inhibition of human CSE using varying levels of L-Cys as substrate and fixed PLP levels | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 19. | ALA4675289 | B | Effect on PLP interaction with human CSE assessed as effect on spectra of CSE-bound PLP | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4675290 | B | Non-competitive inhibition of human CSE using varying levels of PLP and fixed L-Cys as substrate | Homo sapiens | 1 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!