| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4202267 | B | Displacement of N-Flu-DOT1L from MBP-tagged ENL (unknown origin) (489 to 559 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs by fluorescence polarization assay | Homo sapiens | 28 | assay format | Scientific Literature | ||
| 2. | ALA4202269 | B | Binding affinity to MBP-tagged ENL (unknown origin) (489 to 559 residues) expressed in Escherichia coli BL21(DE3) by Bio-layer interferometry | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 3. | ALA4265379 | B | Binding affinity to recombinant C-terminal His6-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in expressed Escherichia coli Rosetta assessed as change in melting temperature by thermal shift assay | Homo sapiens | 19 | assay format | Scientific Literature | ||
| 4. | ALA4265380 | B | Binding affinity to recombinant C-terminal His6-tagged ENL YEATS domain (1 to 148 residues) (unknown origin) expressed in expressed Escherichia coli Rosetta by ITC assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 5. | ALA4411218 | B | Inhibition of human MLLT1 by alphascreen assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4411219 | B | Binding affinity to human MLLT1 by isothermal titration calorimetry | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4411220 | B | Binding affinity to C-terminal His6-tagged MLLT1 YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli Rosetta by isothermal titration calorimetry | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 8. | ALA4411221 | B | Inhibition of C-terminal His6-tagged MLLT1 YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli Rosetta by alphascreen assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 9. | ALA4411222 | B | Binding affinity to C-terminal His6-tagged MLLT1 YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli Rosetta assessed as change in enthalpy by isothermal titration calorimetry | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 10. | ALA4411223 | B | Binding affinity to C-terminal His6-tagged MLLT1 YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli Rosetta assessed as change in entropy by isothermal titration calorimetry | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 11. | ALA4411224 | B | Binding affinity to C-terminal His6-tagged MLLT1 YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli Rosetta assessed as change in Gibb's free energy by isothermal titration calorimetry | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 12. | ALA4810338 | B | Inhibition of human His-ENL YEATS domain and biotinylated H3K9ac peptide interaction by AlphaScreen assay | Homo sapiens | 28 | single protein format | Scientific Literature | ||
| 13. | ALA4810339 | B | Binding affinity to human His-ENL YEATS domain assessed as dissociation constant by SPR analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 14. | ALA4810344 | B | Inhibition of human His-ENL YEATS domain and biotinylated H3K9ac peptide interaction at 1 uM by AlphaScreen assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 15. | ALA4810345 | B | Inhibition of human His-ENL YEATS domain and biotinylated H3K9ac peptide interaction at 5 uM by AlphaScreen assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 16. | ALA4810353 | B | Stabilization of ENL in human MV4-11 cells assessed as inhibition of high temperature-induced ENL protein degradation at 20 uM incubated for 5 hrs by cellular thermal shift assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4810354 | B | Stabilization of ENL in human MOLM13 cells assessed as inhibition of high temperature-induced ENL protein degradation at 20 uM incubated for 5 hrs by cellular thermal shift assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4810355 | B | Stabilization of GAS41 in human MV4-11 cells assessed as inhibition of high temperature-induced GAS41 protein degradation at 20 uM incubated for 5 hrs by cellular thermal shift assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4810356 | B | Stabilization of GAS41 in human MOLM13 cells assessed as inhibition of high temperature-induced GAS41 protein degradation at 20 uM incubated for 5 hrs by cellular thermal shift assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4810357 | B | Stabilization of ENL in human HeLa cells assessed as inhibition of high temperature-induced ENL protein degradation at 20 uM incubated for 5 hrs by cellular thermal shift assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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