# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA935755 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyl-uronamide from mouse recombinant adenosine A1 receptor expressed in HEK293 cells | Mus musculus | 23 | ALA1145629 | cell-based format | Scientific Literature | |
2. | ALA1068173 | B | Binding affinity to mouse adenosine A1 receptor | Mus musculus | 3 | ALA1157642 | single protein format | Scientific Literature | |
3. | ALA2067573 | B | Displacement of [3H]CGS21680 from mouse adenosine A1 receptor expressed in HEK293 cells at 10 uM after 60 mins by liquid scintillation counting | Mus musculus | 10 | ALA2062514 | cell-based format | Scientific Literature | |
4. | ALA2067580 | B | Displacement of [3H]CGS21680 from mouse adenosine A1 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting | Mus musculus | 1 | ALA2062514 | cell-based format | Scientific Literature | |
5. | ALA2404653 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from mouse adenosine A1 receptor expressed in HEK293 cell membranes at 10 uM after 60 mins by liquid scintillation counting analysis relative to control | Mus musculus | 9 | ALA2401698 | cell-based format | Scientific Literature | |
6. | ALA2404654 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from mouse adenosine A1 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation counting analysis | Mus musculus | 3 | ALA2401698 | cell-based format | Scientific Literature | |
7. | ALA2406815 | F | Agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA relative to control | Mus musculus | 1 | ALA2401698 | cell-based format | Scientific Literature | |
8. | ALA2406816 | F | Agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA | Mus musculus | 1 | ALA2401698 | cell-based format | Scientific Literature | |
9. | ALA2406817 | F | Partial agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA relative to 2-chloro-N6-cyclopentyladenosine | Mus musculus | 1 | ALA2401698 | cell-based format | Scientific Literature | |
10. | ALA2406818 | F | Partial agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA relative to control | Mus musculus | 1 | ALA2401698 | cell-based format | Scientific Literature | |
11. | ALA2406819 | F | Partial agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA | Mus musculus | 1 | ALA2401698 | cell-based format | Scientific Literature | |
12. | ALA2403960 | F | Agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production up to 10 uM preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA | Mus musculus | 1 | ALA2401698 | cell-based format | Scientific Literature | |
13. | ALA3131096 | B | Inhibition of binding of wild type mBIMBH3 peptide to mouse adenosine A1 receptor by surface plasmon resonance competition experiment | Mus musculus | 2 | ALA3124762 | single protein format | Scientific Literature | |
14. | ALA3413617 | B | Displacement of [3H]R-PIA from mouse A1 adenosine receptor expressed in CHO cells at 10 uM after 60 mins by liquid scintillation counting | Mus musculus | 6 | ALA3407461 | cell-based format | Scientific Literature | |
15. | ALA4152688 | F | Antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of 1 uM CCPA-induced reduction in rhythmic spontaneous contractions by measuring tissue response at 1 uM after 1 hr (Rvb = 20%) | Mus musculus | 1 | ALA4152191 | assay format | Scientific Literature | |
16. | ALA4152689 | F | Antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of 0.1 uM CCPA-induced reduction in rhythmic spontaneous contractions by measuring tissue response at 1 uM after 1 hr (Rvb = 65%) | Mus musculus | 1 | ALA4152191 | assay format | Scientific Literature | |
17. | ALA4152690 | F | Antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of CCPA-induced reduction in rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 6 | ALA4152191 | assay format | Scientific Literature | |
18. | ALA4152691 | F | Reversible antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of CCPA-induced reduction in rhythmic spontaneous contractions at 1 uM incubated for 1 hr measured after compound wash out | Mus musculus | 1 | ALA4152191 | assay format | Scientific Literature | |
19. | ALA4152692 | F | Activity at adenosine A1 receptor in BALB/C mouse ileum assessed as effect on amplitude of rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 5 | ALA4152191 | assay format | Scientific Literature | |
20. | ALA4152693 | F | Activity at adenosine A1 receptor in BALB/C mouse ileum assessed as effect on frequency of rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 5 | ALA4152191 | assay format | Scientific Literature |