| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2067573 | B | Displacement of [3H]CGS21680 from mouse adenosine A1 receptor expressed in HEK293 cells at 10 uM after 60 mins by liquid scintillation counting | Mus musculus | 10 | cell-based format | Scientific Literature | ||
| 2. | ALA2067580 | B | Displacement of [3H]CGS21680 from mouse adenosine A1 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA935755 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyl-uronamide from mouse recombinant adenosine A1 receptor expressed in HEK293 cells | Mus musculus | 23 | cell-based format | Scientific Literature | ||
| 4. | ALA1068173 | B | Binding affinity to mouse adenosine A1 receptor | Mus musculus | 3 | single protein format | Scientific Literature | ||
| 5. | ALA2404653 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from mouse adenosine A1 receptor expressed in HEK293 cell membranes at 10 uM after 60 mins by liquid scintillation counting analysis relative to control | Mus musculus | 9 | cell-based format | Scientific Literature | ||
| 6. | ALA2404654 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from mouse adenosine A1 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation counting analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA2406815 | F | Agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2406816 | F | Agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2406817 | F | Partial agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA relative to 2-chloro-N6-cyclopentyladenosine | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2406818 | F | Partial agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA2406819 | F | Partial agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2403960 | F | Agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production up to 10 uM preincubated for 30 mins prior to forskolin-treatment measured after 15 mins by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3131096 | B | Inhibition of binding of wild type mBIMBH3 peptide to mouse adenosine A1 receptor by surface plasmon resonance competition experiment | Mus musculus | 2 | single protein format | Scientific Literature | ||
| 14. | ALA3413617 | B | Displacement of [3H]R-PIA from mouse A1 adenosine receptor expressed in CHO cells at 10 uM after 60 mins by liquid scintillation counting | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 15. | ALA4152688 | F | Antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of 1 uM CCPA-induced reduction in rhythmic spontaneous contractions by measuring tissue response at 1 uM after 1 hr (Rvb = 20%) | Mus musculus | 1 | assay format | Scientific Literature | ||
| 16. | ALA4152689 | F | Antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of 0.1 uM CCPA-induced reduction in rhythmic spontaneous contractions by measuring tissue response at 1 uM after 1 hr (Rvb = 65%) | Mus musculus | 1 | assay format | Scientific Literature | ||
| 17. | ALA4152690 | F | Antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of CCPA-induced reduction in rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 6 | assay format | Scientific Literature | ||
| 18. | ALA4152691 | F | Reversible antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of CCPA-induced reduction in rhythmic spontaneous contractions at 1 uM incubated for 1 hr measured after compound wash out | Mus musculus | 1 | assay format | Scientific Literature | ||
| 19. | ALA4152692 | F | Activity at adenosine A1 receptor in BALB/C mouse ileum assessed as effect on amplitude of rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 5 | assay format | Scientific Literature | ||
| 20. | ALA4152693 | F | Activity at adenosine A1 receptor in BALB/C mouse ileum assessed as effect on frequency of rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 5 | assay format | Scientific Literature |
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