# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4158454 | B | Inhibition of TRPC4 (unknown origin) | Homo sapiens | 1 | ALA4152379 | single protein format | Scientific Literature | |
2. | ALA4377064 | B | Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in englerin A-induced calcium entry incubated for 30 mins by Fluo-4AM dye based fluorescence assay | Homo sapiens | 1 | ALA4376804 | cell-based format | Scientific Literature | |
3. | ALA4377067 | B | Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in sphingosine-1-phosphate-induced current at -100 mV by patch clamp assay | Homo sapiens | 1 | ALA4376804 | cell-based format | Scientific Literature | |
4. | ALA4377068 | B | Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in sphingosine-1-phosphate-induced current at +100 mV by patch clamp assay | Homo sapiens | 1 | ALA4376804 | cell-based format | Scientific Literature | |
5. | ALA4377070 | B | Inhibition of human TRPC4 expressed in human T-REx-293 cells coexpressing M1 receptor assessed as reduction in calcium influx by Fluo-4AM dye based assay | Homo sapiens | 1 | ALA4376804 | cell-based format | Scientific Literature | |
6. | ALA4377094 | B | Inhibition of TRPC4 (unknown origin) expressed in HEK293 cells assessed as reduction in englerin A-induced current at 5 uM measured every 10 secs by outside-out patches based electrophysiology assay relative to control | Homo sapiens | 1 | ALA4376804 | cell-based format | Scientific Literature | |
7. | ALA4410992 | B | Inhibition of Englerin-activated human TRPC4 channel expressed in HEK293 cells by Q-patch clamp assay | Homo sapiens | 1 | ALA4406916 | cell-based format | Scientific Literature | |
8. | ALA4828438 | B | Antagonist activity at human TRPC4 at <= 30 uM | Homo sapiens | 1 | ALA4825762 | single protein format | Scientific Literature | |
9. | ALA5129287 | B | Inhibition of human TRPC4 channel expressed in HEK293 cells assessed as inhibition of EA-evoked Calcium influx by measuring reduction in intracellular Ca2+ level and measured upto 360 sec by Fluo-4/AM dye based FLIPR assay | Homo sapiens | 2 | ALA5126584 | cell-based format | Scientific Literature | |
10. | ALA5145640 | B | Inhibition of TRPC4 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of EA-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA5143583 | cell-based format | Scientific Literature | |
11. | ALA5149870 | B | Agonist activity at human TRPC4 stably expressed in T-REx-293 cells assessed as increase in calcium flux at 10 uM by Fura-2AM dye based fluorescence plate reader assay relative to control | Homo sapiens | 1 | ALA5143752 | cell-based format | Scientific Literature | |
12. | ALA5149871 | B | Agonist activity at human TRPC4 stably expressed in T-REx-293 cells assessed as increase in calcium flux at 10 uM by Fura-2AM dye based fluorescence plate reader assay | Homo sapiens | 4 | ALA5143752 | cell-based format | Scientific Literature |