| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4234429 | B | Inhibition of glycolate oxidase in mouse Agxt1-/- hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 72 hrs by sulfonated-DCIP dye-based assay | Mus musculus | 1 | ALA4229456 | cell-based format | Scientific Literature | |
| 2. | ALA4234430 | B | Inhibition of glycolate oxidase in mouse Agxt1-/- hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 48 hrs by sulfonated-DCIP dye-based assay | Mus musculus | 1 | ALA4229456 | cell-based format | Scientific Literature | |
| 3. | ALA4234431 | B | Inhibition of glycolate oxidase in mouse Agxt1-/- hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 24 hrs by sulfonated-DCIP dye-based assay | Mus musculus | 1 | ALA4229456 | cell-based format | Scientific Literature | |
| 4. | ALA4234432 | B | Inhibition of mouse N-terminal His-tagged glycolate oxidase expressed in BL21(DE3) Escherichia coli using glycolate as substrate by Cornish-Bowden plot analysis | Mus musculus | 1 | ALA4229456 | assay format | Scientific Literature | |
| 5. | ALA4234433 | B | Inhibition of mouse recombinant glycolate oxidase expressed in Escherichia coli at 25 uM using glycolate as substrate after 1 min by sulfonated DCIP dye-based assay relative to control | Mus musculus | 53 | ALA4229456 | assay format | Scientific Literature | |
| 6. | ALA4234434 | B | Inhibition of mouse recombinant glycolate oxidase expressed in Escherichia coli using glycolate as substrate by sulfonated DCIP dye-based assay | Mus musculus | 25 | ALA4229456 | assay format | Scientific Literature | |
| 7. | ALA4234435 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as relative oxalate level at 10 uM after 24 hrs | Mus musculus | 43 | ALA4229456 | cell-based format | Scientific Literature | |
| 8. | ALA4234436 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as relative oxalate level at 12.5 uM after 24 hrs | Mus musculus | 1 | ALA4229456 | cell-based format | Scientific Literature | |
| 9. | ALA4234437 | B | Inhibition of mouse recombinant glycolate oxidase expressed in Escherichia coli using glycolate as substrate by Dixon plot and Cornish-Bowden plot analysis | Mus musculus | 1 | ALA4229456 | assay format | Scientific Literature | |
| 10. | ALA4234438 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production at 12.5 uM after 24 hrs post treatment relative to control | Mus musculus | 1 | ALA4229456 | cell-based format | Scientific Literature | |
| 11. | ALA4234439 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production at 6.25 uM after 24 hrs post treatment relative to control | Mus musculus | 1 | ALA4229456 | cell-based format | Scientific Literature | |
| 12. | ALA4234440 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production at 12.5 uM after 48 hrs post treatment relative to control | Mus musculus | 1 | ALA4229456 | cell-based format | Scientific Literature | |
| 13. | ALA4234442 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 24 hrs | Mus musculus | 2 | ALA4229456 | cell-based format | Scientific Literature | |
| 14. | ALA4234443 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 48 hrs | Mus musculus | 2 | ALA4229456 | cell-based format | Scientific Literature | |
| 15. | ALA4234444 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 72 hrs | Mus musculus | 2 | ALA4229456 | cell-based format | Scientific Literature | |
| 16. | ALA4234445 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production at 2.5 uM after 24 hrs post treatment relative to control | Mus musculus | 1 | ALA4229456 | cell-based format | Scientific Literature | |
| 17. | ALA4234446 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production at 5 uM after 72 hrs post treatment | Mus musculus | 1 | ALA4229456 | cell-based format | Scientific Literature | |
| 18. | ALA4234448 | B | Potency index, ratio of EC50 for CCPST to EC50 for test compound for inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 24 to 72 hrs | Mus musculus | 2 | ALA4229456 | cell-based format | Scientific Literature | |
| 19. | ALA4234449 | B | Potency index, ratio of EC50 for CCPST to EC50 for test compound for inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 24 hrs | Mus musculus | 1 | ALA4229456 | cell-based format | Scientific Literature | |
| 20. | ALA4234457 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production at 10 uM after 24 hrs | Mus musculus | 3 | ALA4229456 | cell-based format | Scientific Literature |
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