# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4194657 | B | Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analysis | Rattus norvegicus | 1 | ALA4190374 | cell-based format | Scientific Literature | |
2. | ALA4194670 | B | Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3gamma2 expressed in HEK293 cell membranes up to 10 uM after 90 mins by liquid scintillation counting analysis relative to control | Rattus norvegicus | 2 | ALA4190374 | cell-based format | Scientific Literature | |
3. | ALA4194680 | B | Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3gamma2 expressed in HEK293 cell membranes at 20 uM after 90 mins by liquid scintillation counting analysis relative to control | Rattus norvegicus | 1 | ALA4190374 | cell-based format | Scientific Literature | |
4. | ALA4194709 | B | Agonist activity at rat eGFP-fused GABA-A receptor alpha4beta3gamma2 expressed in HEK293 cells assessed as ratio of I0 to GABA Imax at 10 uM in absence of GABA by patch-clamp assay | Rattus norvegicus | 2 | ALA4190374 | cell-based format | Scientific Literature | |
5. | ALA4194719 | B | Modulation of rat eGFP-fused GABA-A receptor alpha4beta3gamma2 expressed in HEK293 cells at <=1 uM in presence of GABA by patch-clamp assay relative to control | Rattus norvegicus | 2 | ALA4190374 | cell-based format | Scientific Literature |