| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5254715 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as activation of maximal current at -80 mV holding potential in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5254718 | B | Positive allosteric modulation of rat recombinant GABAA beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal current at -80 mV holding potential in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4194659 | B | Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analysis | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4194672 | B | Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes up to 10 uM after 90 mins by liquid scintillation counting analysis relative to control | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA4194682 | B | Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes at 20 uM after 90 mins by liquid scintillation counting analysis relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4194694 | B | Modulation of rat eGFP-fused GABA-A receptor alpha6beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4194702 | B | Modulation of rat eGFP-fused GABA-A receptor alpha6beta3 expressed in HEK293 cells up to 10 uM in presence of GABA by patch-clamp assay relative to control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4194711 | B | Agonist activity at rat eGFP-fused GABA-A receptor alpha6beta3 expressed in HEK293 cells assessed as ratio of I0 to GABA Imax at 10 uM in absence of GABA by patch-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4194714 | B | Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid scintillation counting analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4194718 | B | Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes at 10 uM after 90 mins by liquid scintillation counting analysis relative to control | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4194728 | B | Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes up to 20 uM after 90 mins by liquid scintillation counting analysis relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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