| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4194666 | B | Displacement of [3H]EBOB from rat GABA-A receptor alpha1beta3 expressed in HEK293 cell membranes at 10 uM after 90 mins by liquid scintillation counting analysis relative to control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4194689 | B | Modulation of rat eGFP-fused GABA-A receptor alpha1beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4194697 | B | Modulation of rat eGFP-fused GABA-A receptor alpha1beta3 expressed in HEK293 cells up to 10 uM in presence of GABA by patch-clamp assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4194705 | B | Agonist activity at rat eGFP-fused GABA-A receptor alpha1beta3 expressed in HEK293 cells assessed as ratio of I0 to GABA Imax at 10 uM in absence of GABA by patch-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4194721 | B | Modulation of rat eGFP-fused GABA-A receptor alpha1beta3 expressed in HEK293 cells at <= 10 uM in presence of GABA by patch-clamp assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4367977 | B | Positive allosteric modulator activity at rat alpha1beta3 GABA-A receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced chloride current at 30 uM co-applied with GABA at concentration of EC3-5 at -60 mV holding potential by two-microelectrode voltage clamp method relative to control | Rattus norvegicus | 9 | cell-based format | Scientific Literature | ||
| 7. | ALA4367978 | B | Positive allosteric modulator activity at rat alpha1beta3 GABA-A receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced chloride current at 10 uM co-applied with GABA at concentration of EC3-5 at -60 mV holding potential by two-microelectrode voltage clamp method relative to control | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA4367980 | B | Positive allosteric modulator activity at rat alpha1beta3 GABA-A receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced chloride current at 1 to 30 uM co-applied with GABA at concentration of EC3-5 at -60 mV holding potential by two-microelectrode voltage clamp method relative to control | Rattus norvegicus | 5 | cell-based format | Scientific Literature |
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